Gene: TBC1D30
Official Full Name: TBC1 domain family member 30provided by HGNC
Gene Summary: Enables GTPase activator activity and small GTPase binding activity. Involved in negative regulation of cilium assembly and positive regulation of GTPase activity. Located in ciliary basal body; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29444 | TBC1D30 Knockout cell line (HeLa) | Human | TBC1D30 | 1:3~1:6 | Negative | Online Inquiry |
KO29445 | TBC1D30 Knockout cell line (HCT 116) | Human | TBC1D30 | 1:2~1:4 | Negative | Online Inquiry |
KO29446 | TBC1D30 Knockout cell line (HEK293) | Human | TBC1D30 | 1:3~1:6 | Negative | Online Inquiry |
KO29447 | TBC1D30 Knockout cell line (A549) | Human | TBC1D30 | 1:3~1:4 | Negative | Online Inquiry |
TBC1D30 Gene Knockout Cell Lines are advanced experimental tools designed for the study of cellular mechanisms associated with the TBC1D30 gene, known for its pivotal role in regulating intracellular transport and protein trafficking. These cell lines have been genetically modified using CRISPR-Cas9 technology, leading to the precise knockout of the TBC1D30 gene, thereby enabling researchers to dissect the functional implications of its absence in various cellular pathways.
The primary function of these knockout cell lines revolves around their use in elucidating the molecular mechanisms governing autophagy, endocytosis, and exocytosis processes. By comparing the behavior of TBC1D30 knockout cells to wild-type counterparts, researchers can observe alterations in vesicle trafficking, protein localization, and overall cellular homeostasis. This provides a unique opportunity to explore how dysregulation of these pathways can contribute to various diseases, including neurodegenerative disorders and metabolic syndromes.
The scientific importance of TBC1D30 Gene Knockout Cell Lines extends beyond basic research; they are invaluable in drug discovery and validation processes. By utilizing these cell lines, researchers can assess the impact of potential therapeutics on cellular functions disrupted by the loss of TBC1D30. Additionally, clinical applications can emerge from studying the gene's involvement in diseases, potentially leading to targeted therapies and improved patient outcomes.
What sets TBC1D30 Gene Knockout Cell Lines apart from traditional models is their precision and reliability, essential for reproducibility in scientific experiments. Unlike broad gene knockdown approaches, CRISPR-mediated knockout offers a definitive genetic alteration that creates a consistent platform for experimentation. This specificity minimizes background noise, enhancing the clarity of biological findings.
For researchers and clinicians aiming to deepen their understanding of cellular mechanisms and develop innovative therapies, TBC1D30 Gene Knockout Cell Lines provide a robust and scientifically validated resource. Our company's expertise in CRISPR technology and deep commitment to advancing biological research ensures that we provide high-quality, accurately characterized products that meet the needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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