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TAMM41 Knockout Cell Lines

Gene: TAMM41

Official Full Name: TAM41 mitochondrial translocator assembly and maintenance homologprovided by HGNC

Gene Summary: Predicted to enable phosphatidate cytidylyltransferase activity. Predicted to be involved in CDP-diacylglycerol biosynthetic process and cardiolipin biosynthetic process. Is active in mitochondrion. Implicated in combined oxidative phosphorylation deficiency 56. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26545 TAMM41 Knockout cell line (HeLa) Human TAMM41 1:3~1:6 Negative Online Inquiry
KO26546 TAMM41 Knockout cell line (HCT 116) Human TAMM41 1:2~1:4 Negative Online Inquiry
KO26547 TAMM41 Knockout cell line (HEK293) Human TAMM41 1:3~1:6 Negative Online Inquiry

Background

TAMM41 Gene Knockout Cell Lines are state-of-the-art cellular models specifically engineered to lack the expression of the TAMM41 gene, a crucial component involved in mitochondrial function and morphology. This product allows researchers to investigate the biological implications of TAMM41 depletion, thus providing valuable insights into mitochondrial dynamics, bioenergetics, and the processes of apoptosis and cell stress response. The generation of these knockout cell lines employs advanced CRISPR/Cas9 technology, ensuring precise gene editing and a high rate of efficiency in gene disruption.

The fundamental mechanism by which these cell lines operate centers around the interplay between mitochondrial biogenesis and cellular energy production. By observing the metabolic changes and cellular behaviors in TAMM41-deficient cells, researchers can elucidate the gene's role in mitochondrial maintenance, energy metabolism, and its broader implications in diseases such as neurodegeneration and metabolic disorders. This precise knockout approach presents a significant opportunity for both basic research and translational applications in uncovering the underlying mechanisms of various pathologies linked to mitochondrial dysfunction.

The scientific importance of TAMM41 Gene Knockout Cell Lines cannot be overstated. They serve as vital tools for pharmacological studies, potential drug discovery processes, and developing targeted therapies that address mitochondrial-related diseases. Compared to other models, our cell lines offer distinctive advantages, such as enhanced specificity and reproducibility, minimizing off-target effects often seen with older methods.

For researchers and clinicians alike, utilizing TAMM41 Gene Knockout Cell Lines means gaining access to a reliable and innovative platform for advancing their studies. By integrating this valuable resource into their work, users can accelerate their understanding of critical biological processes that could lead to significant medical breakthroughs.

Our company specializes in providing high-quality biological products, and with a strong commitment to excellence and customer satisfaction, we ensure that our cell lines are of unparalleled quality, tailored for the unique needs of the scientific community. We are proud to support your research endeavors with these advanced biological tools.

Please note that all services are for research use only. Not intended for any clinical use.

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