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SYTL4 Knockout Cell Lines

Gene: SYTL4

Official Full Name: synaptotagmin like 4provided by HGNC

Gene Summary: This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22065 SYTL4 Knockout cell line (HeLa) Human SYTL4 1:3~1:6 Negative Online Inquiry
KO22066 SYTL4 Knockout cell line (HCT 116) Human SYTL4 1:2~1:4 Negative Online Inquiry
KO22067 SYTL4 Knockout cell line (HEK293) Human SYTL4 1:3~1:6 Negative Online Inquiry
KO22068 SYTL4 Knockout cell line (A549) Human SYTL4 1:3~1:4 Negative Online Inquiry

Background

SYTL4 Gene Knockout Cell Lines are specialized cell lines engineered to lack the expression of the SYTL4 gene, which encodes a protein involved in intracellular trafficking and membrane dynamics. These knockout cell lines provide a critical tool for researchers studying the functional roles of SYTL4 in various biological processes, such as cell signaling, endocytosis, and neuronal function.

The key mechanism of action involves the complete ablation of the SYTL4 gene, achieved through CRISPR/Cas9 gene-editing technology, which ensures precise modifications within the genome. By using these cell lines, scientists can investigate the downstream effects of SYTL4 absence on cellular behaviors, including but not limited to vesicular transport, molecule secretion, and synaptic transmission, thereby elucidating the gene’s biological significance.

The scientific importance of SYTL4 Gene Knockout Cell Lines extends to various research areas, particularly neurobiology, cancer biology, and developmental biology. Researchers can utilize these cell lines as models to understand the genetic underpinnings of neurological disorders, cancer cell metastasis, and the immune response. Additionally, the insights gained from these studies have potential clinical implications for developing targeted therapies and understanding disease mechanisms.

Different from alternative models, SYTL4 Gene Knockout Cell Lines offer highly specific and reproducible results due to their targeted gene disruption, which reduces off-target effects found in less precise models. Moreover, these cell lines are readily available in a variety of formats that have been extensively validated and characterized, ensuring that researchers can trust their findings.

For researchers and clinicians, integrating SYTL4 Gene Knockout Cell Lines into studies unlocks new pathways of inquiry that are crucial for advancing our understanding of cellular and molecular mechanisms. With access to these models, investigators can confidently explore innovative therapeutic strategies.

Our company brings years of expertise in genetic engineering and cell line development, and we pride ourselves on delivering high-quality biological tools that empower the scientific community in their search for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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