Gene: SLC38A3
Official Full Name: solute carrier family 38 member 3provided by HGNC
Gene Summary: Enables L-amino acid transmembrane transporter activity. Involved in carboxylic acid transport. Located in plasma membrane. Implicated in developmental and epileptic encephalopathy 102. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31348 | SLC38A3 Knockout cell line (HCT 116) | Human | SLC38A3 | 1:2~1:4 | Negative | Online Inquiry |
SLC38A3 Gene Knockout Cell Lines are precisely engineered cellular models that serve as valuable tools for studying the physiological and pathological roles of the SLC38A3 gene, which encodes a sodium-coupled neutral amino acid transporter. By utilizing CRISPR-Cas9 technology, these cell lines have been generated to effectively disrupt the SLC38A3 gene function, thereby allowing researchers to investigate the consequences of its loss on cellular metabolism, amino acid transport, and overall cell homeostasis.
The SLC38A3 transporter plays a crucial role in regulating intracellular amino acid levels and is implicated in various cellular responses, including nutrient sensing and signal transduction pathways. By utilizing these knockout cell lines, scientists can elucidate the gene's impact on process like metabolic regulation, stress responses, and other physiological functions. Consequently, these models hold significant scientific importance, as they provide insights into the gene's involvement in diseases such as obesity, diabetes, and neurodegenerative disorders.
What sets SLC38A3 Gene Knockout Cell Lines apart from other models is their specificity and accuracy in gene editing, which enables a more controlled environment for experimental analysis. Unlike traditional methods that may only partially inhibit gene function, these knockout lines completely eliminate the target gene's expression, yielding clear and reproducible results that drive impactful research forward. Moreover, the versatility of these cell lines allows for a wide range of applications in both basic research and clinical investigations.
Researchers and clinicians alike will find these cell lines invaluable for developing therapeutic strategies aimed at modulating amino acid transport mechanisms. By elucidating the role of the SLC38A3 gene in health and disease, these models can significantly contribute to the understanding of metabolic disorders and provide foundations for targeted therapies.
At [Your Company Name], we are dedicated to advancing biological research by providing cutting-edge tools like the SLC38A3 Gene Knockout Cell Lines, backed by our expertise in genetic engineering and cellular biology. Our commitment to quality ensures that researchers gain reliable models for their exploration of complex biological phenomena.
Please note that all services are for research use only. Not intended for any clinical use.
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