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SLC25A23 Knockout Cell Lines

Gene: SLC25A23

Official Full Name: solute carrier family 25 member 23provided by HGNC

Gene Summary: Enables ADP:phosphate antiporter activity and ATP:phosphate antiporter activity. Involved in mitochondrial transmembrane transport; positive regulation of mitochondrial calcium ion concentration; and regulation of cellular hyperosmotic salinity response. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20258 SLC25A23 Knockout cell line (HeLa) Human SLC25A23 1:3~1:6 Negative Online Inquiry
KO20259 SLC25A23 Knockout cell line (HCT 116) Human SLC25A23 1:2~1:4 Negative Online Inquiry
KO20260 SLC25A23 Knockout cell line (HEK293) Human SLC25A23 1:3~1:6 Negative Online Inquiry
KO20261 SLC25A23 Knockout cell line (A549) Human SLC25A23 1:3~1:4 Negative Online Inquiry

Background

SLC25A23 Gene Knockout Cell Lines are genetically engineered cell lines characterized by the targeted deletion of the SLC25A23 gene, which encodes a mitochondrial transporter involved in the exchange of metabolites and maintaining mitochondrial function. This innovative product allows researchers to study the physiological and pathological roles of SLC25A23, providing critical insights into cellular metabolism, mitochondrial dynamics, and associated diseases.

The cell lines operated by mechanisms that elucidate how the loss of SLC25A23 affects cellular metabolism, specifically highlighting changes in mitochondrial energy production and metabolic adaptations. By implementing CRISPR/Cas9 technology for gene knockout, these cell lines serve as a precise tool for exploring the consequences of SLC25A23 deficiency, including alterations in energy homeostasis, oxidative stress responses, and the metabolic shifts that may contribute to disease states.

The scientific importance of SLC25A23 Gene Knockout Cell Lines extends to various applications in research, particularly in the study of metabolic disorders, mitochondrial diseases, and their role in cancer biology. These cell lines facilitate the investigation into therapeutic targets and the potential development of novel treatments aimed at restoring mitochondrial function in pathogenic scenarios.

Compared to alternative models, such as wild-type or less targeted knockout cell lines, SLC25A23 Gene Knockout Cell Lines provide a more accurate representation of the gene's role within the context of a living system. Their specificity reduces background variability and enhances the robustness of experimental results, ensuring credible data for foundational and applied research.

For researchers and clinicians engaged in metabolic and mitochondrial studies, these knockout cell lines represent an invaluable resource that accelerates discovery and innovation. Understanding the mechanistic pathways influenced by SLC25A23 could lead to breakthroughs in combating various diseases linked to mitochondrial dysfunction.

Our company, with a robust portfolio in gene editing and cellular models, is committed to providing high-quality and reliable biological products that empower researchers to advance their studies effectively. Our expertise in genetic engineering leverages the latest technologies to ensure our offerings are at the forefront of biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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