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SH3PXD2A Knockout Cell Lines

Gene: SH3PXD2A

Official Full Name: SH3 and PX domains 2Aprovided by HGNC

Gene Summary: Predicted to enable superoxide-generating NADPH oxidase activator activity. Involved in osteoclast fusion and superoxide metabolic process. Located in podosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32993 SH3PXD2A Knockout cell line (HeLa) Human SH3PXD2A 1:3~1:6 Negative Online Inquiry
KO32994 SH3PXD2A Knockout cell line (HCT 116) Human SH3PXD2A 1:2~1:4 Negative Online Inquiry
KO32995 SH3PXD2A Knockout cell line (HEK293) Human SH3PXD2A 1:3~1:6 Negative Online Inquiry
KO32996 SH3PXD2A Knockout cell line (A549) Human SH3PXD2A 1:3~1:4 Negative Online Inquiry

Background

SH3PXD2A Gene Knockout Cell Lines are genetically modified cellular models specifically designed to study the function of the SH3PXD2A gene, which encodes a protein involved in cellular signaling, cytoskeletal dynamics, and various cellular processes. These knockout cell lines are engineered to provide a precise removal of the SH3PXD2A gene, allowing researchers to analyze the phenotypic and molecular consequences of its absence. By eliminating this gene, the cell lines facilitate in-depth investigations into the role of SH3PXD2A in disease states, particularly in cancer progression and metastasis.

The primary mechanism at work in SH3PXD2A Gene Knockout Cell Lines involves disrupting the normal biological pathways regulated by the SH3PXD2A protein. This disruption allows for a clearer understanding of how SH3PXD2A contributes to mechanisms such as cell migration, adhesion, and invasion, which are critical in the context of cancer biology. Researchers leveraging these cell lines can elucidate the downstream effects of SH3PXD2A deletion on various signaling pathways, providing insight into potential therapeutic targets.

In both research and clinical settings, SH3PXD2A Gene Knockout Cell Lines hold significant scientific importance. With the capacity to model disease mechanisms accurately, they can be utilized in drug discovery and development, particularly in assessing efficacy and safety profiles of new compounds targeting the pathways influenced by the SH3PXD2A gene. These models can also serve in biomarker discovery, enhancing patient stratification in clinical trials.

What sets SH3PXD2A Gene Knockout Cell Lines apart from other cellular models is their specificity and precision. By eliminating the SH3PXD2A gene, researchers can avoid the off-target effects commonly associated with siRNA or CRISPR technologies, thus ensuring the fidelity of experimental results. Furthermore, these knockout lines are easily accessible and compatible with a variety of assays, streamlining the research process.

For researchers and clinicians, the value of SH3PXD2A Gene Knockout Cell Lines is profound; they provide a powerful tool to dissect the role of SH3PXD2A in health and disease, paving the way for novel insights into therapeutic interventions. Our company specializes in the development of high-quality genetic tools for advancing biological research, ensuring scientists have the resources they need to drive innovation and discovery in their fields.

Please note that all services are for research use only. Not intended for any clinical use.

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