Gene: SH3KBP1
Official Full Name: SH3 domain containing kinase binding protein 1provided by HGNC
Gene Summary: This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26820 | SH3KBP1 Knockout cell line (HeLa) | Human | SH3KBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO26821 | SH3KBP1 Knockout cell line (HCT 116) | Human | SH3KBP1 | 1:2~1:4 | Negative | Online Inquiry |
KO26822 | SH3KBP1 Knockout cell line (HEK293) | Human | SH3KBP1 | 1:3~1:6 | Negative | Online Inquiry |
KO26823 | SH3KBP1 Knockout cell line (A549) | Human | SH3KBP1 | 1:3~1:4 | Negative | Online Inquiry |
SH3KBP1 Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to lack the SH3KBP1 (SH3-domain kinase binding protein 1) gene. This protein plays a critical role in various cellular processes, including signal transduction, cytoskeletal remodeling, and cellular adhesion. By knocking out the SH3KBP1 gene, researchers can investigate the multifaceted roles this protein plays in cellular biology, particularly in relation to cancer progression, immune response, and cellular signaling pathways.
The key function of the SH3KBP1 Gene Knockout Cell Lines lies in enabling scientists to explore the mechanistic basis of SH3KBP1's involvement in tumorigenesis and other diseases. The absence of this protein allows for an unobstructed analysis of signaling pathways that normally rely on SH3KBP1 interactions, thereby providing a clearer understanding of its physiological and pathological roles. These knockout cell lines serve as essential tools for elucidating SH3KBP1's cellular functions and assessing potential therapeutic targets.
In terms of scientific importance, the SH3KBP1 Gene Knockout Cell Lines are invaluable in both research and clinical settings. They facilitate the study of cancer biology by allowing researchers to dissect the effects of SH3KBP1 in tumor cell lines, providing insights that may lead to new treatment strategies. Moreover, these cell lines offer a reliable model for studying genetic interactions, drug responses, and the development of resistance mechanisms.
What sets the SH3KBP1 Gene Knockout Cell Lines apart from alternatives is their specificity and reliability. These lines are produced with precision gene-editing techniques, ensuring consistent and reproducible results. Researchers can depend on these cell lines to deliver accurate data that can substantially enhance their studies and accelerate discovery.
For researchers and clinicians alike, the value of utilizing SH3KBP1 Gene Knockout Cell Lines cannot be overstated. Their application spans various fields, from fundamental biology to therapeutic innovation, making them an essential addition to any laboratory focused on cellular signaling and disease mechanisms. Our company prides itself on its state-of-the-art genetic editing technology and extensive experience in developing high-quality biological products, ensuring that our customers have access to the most advanced tools for their research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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