Gene: SFXN5
Official Full Name: sideroflexin 5provided by HGNC
Gene Summary: Predicted to enable citrate transmembrane transporter activity. Predicted to be involved in citrate transport and mitochondrial transmembrane transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00052 | SFXN5 Knockout cell line (Y79) | Human | SFXN5 | 1:2-1:3 | Negative | Online Inquiry |
KO00420 | SFXN5 knockout cell line (HeLa) | Human | SFXN5 | 1:3~1:6 | Negative | Online Inquiry |
KO22079 | SFXN5 Knockout cell line (HCT 116) | Human | SFXN5 | 1:2~1:4 | Negative | Online Inquiry |
KO22080 | SFXN5 Knockout cell line (HEK293) | Human | SFXN5 | 1:3~1:6 | Negative | Online Inquiry |
KO22081 | SFXN5 Knockout cell line (A549) | Human | SFXN5 | 1:3~1:4 | Negative | Online Inquiry |
SFXN5 Gene Knockout Cell Lines are genetically modified cell lines designed to eliminate the expression of the SFXN5 gene, which is implicated in various biological processes, including iron metabolism and cellular responses to oxidative stress. By creating these knockout models, researchers can investigate the precise role of the SFXN5 gene in health and disease, facilitating a deeper understanding of its contribution to pathophysiological conditions such as neurodegeneration, cancer, and metabolic disorders.
The key function of SFXN5 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for studying the effects of gene loss on cellular functions. These cell lines operate through the mechanism of CRISPR-Cas9 technology, which allows for precise genome editing. This process enables researchers to observe alterations in metabolic pathways, changes in iron homeostasis, and shifts in stress response mechanisms, giving insight into the gene's biological significance.
The scientific importance of these knockout cell lines is profound, particularly in the contexts of research and clinical applications. By elucidating the role of SFXN5, scientists can develop targeted therapies or interventions for disorders where this gene plays a critical role. Additionally, these models serve as powerful tools for drug screening and biomarker identification.
Compared to alternative models, such as transient knockdown approaches or traditional knockout mice, SFXN5 Gene Knockout Cell Lines offer enhanced specificity, stability, and ease of use. Researchers can rely on these cell lines to maintain consistent expression profiles over extended periods, which is pivotal for longitudinal studies and complex experimental designs.
For researchers and clinicians aiming to expand their understanding of cellular mechanisms and develop innovative treatments, SFXN5 Gene Knockout Cell Lines represent a valuable resource. Their robust characteristics facilitate the investigation of intricate biological questions, paving the way for breakthroughs in medical science.
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Please note that all services are for research use only. Not intended for any clinical use.
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