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SFXN3 Knockout Cell Lines

Gene: SFXN3

Official Full Name: sideroflexin 3provided by HGNC

Gene Summary: Enables L-serine transmembrane transporter activity. Involved in serine import into mitochondrion. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25644 SFXN3 Knockout cell line (HeLa) Human SFXN3 1:3~1:6 Negative Online Inquiry
KO25645 SFXN3 Knockout cell line (HCT 116) Human SFXN3 1:2~1:4 Negative Online Inquiry
KO25646 SFXN3 Knockout cell line (HEK293) Human SFXN3 1:3~1:6 Negative Online Inquiry
KO25647 SFXN3 Knockout cell line (A549) Human SFXN3 1:3~1:4 Negative Online Inquiry

Background

SFXN3 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the functional role of the SFXN3 gene, which encodes a protein implicated in various cellular processes, including mitochondrial function and iron homeostasis. These knockout cell lines are created through targeted gene editing techniques, enabling researchers to disrupt the expression of SFXN3, thus facilitating investigations into its contributions to cellular physiology and pathology.

The primary mechanism of these knockout cell lines involves the use of CRISPR-Cas9 technology, which allows for precise genomic alterations within the host cell's DNA. By observing the phenotypic and molecular changes arising from the absence of SFXN3, researchers can elucidate its biological roles, making these cell lines invaluable for studies on mitochondrial diseases, metabolic disorders, and neurodegenerative conditions.

In scientific research and clinical applications, SFXN3 Gene Knockout Cell Lines present a unique opportunity for dissecting the complex interactions between genes and their expression patterns. They enable the screening of potential therapeutic agents aimed at modulating SFXN3 activity and can serve as platforms for drug discovery and validation in preclinical settings. The ability to generate isogenic cell lines also minimizes variability in experimental setups, enhancing reproducibility and reliability of results.

Compared to other gene knockout technologies, SFXN3 Gene Knockout Cell Lines offer a streamlined workflow and rapid generation time, making them more efficient for laboratories aiming to explore gene function without extensive resource investment. Their specificity and targeted action reduce off-target effects often seen in traditional knockout methodologies, thus improving experimental accuracy.

For researchers and clinicians-focused on elucidating the impacts of SFXN3 modulation on cellular mechanisms, these knockout cell lines are an indispensable tool that not only accelerate breakthroughs in understanding disease mechanisms but also foster advancements in targeted therapeutic strategies. With a commitment to quality and innovation, our company provides a robust portfolio of genetic tools and resources tailored to meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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