Gene: RBM18
Official Full Name: RNA binding motif protein 18provided by HGNC
Gene Summary: Predicted to enable RNA binding activity. Located in cytosol; intercellular bridge; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23087 | RBM18 Knockout cell line (HeLa) | Human | RBM18 | 1:3~1:6 | Negative | Online Inquiry |
KO23088 | RBM18 Knockout cell line (HCT 116) | Human | RBM18 | 1:2~1:4 | Negative | Online Inquiry |
KO23089 | RBM18 Knockout cell line (HEK293) | Human | RBM18 | 1:3~1:6 | Negative | Online Inquiry |
KO23090 | RBM18 Knockout cell line (A549) | Human | RBM18 | 1:3~1:4 | Negative | Online Inquiry |
RBM18 Gene Knockout Cell Lines are engineered cellular models specifically designed to investigate the role of the RBM18 gene, known for its involvement in RNA binding and regulation of gene expression. These cell lines are generated through precise gene editing techniques, such as CRISPR-Cas9, which effectively disrupt the RBM18 gene. As a result, researchers can explore the biological functions and downstream effects of RBM18 in various cellular contexts.
The primary function of RBM18 is its participation in pre-mRNA splicing and regulation of mRNA turnover, processes crucial for gene expression modulation. By utilizing RBM18 knockout cell lines, scientists can gain insights into alternative splicing events and the resulting impact on cellular function and phenotype. This capability is particularly valuable in understanding the pathways associated with cancer and developmental disorders where RNA processing plays a significant role.
In research and clinical settings, RBM18 knockout cell lines contribute significantly to elucidating pathological mechanisms, allowing for innovative therapeutic strategies targeting splicing-related diseases. The specificity of these models enhances the reliability of experimental results, offering a more accurate representation of the biological implications of RBM18 disruption.
One of the standout advantages of our RBM18 Gene Knockout Cell Lines is their robustness and reproducibility, ensuring consistent performance across experiments. Unlike alternatives that utilize non-specific methods or rely on transient gene silencing, our knockout lines provide stable expression profiles, making them suitable for long-term studies and high-throughput screening.
Researchers and clinicians will find immense value in these cell lines as they pave the way for groundbreaking discoveries in gene regulation and associated diseases. The precise knockout model enables targeted inquiries into RBM18’s role, fostering advancement in the life sciences field.
Our company prides itself on its cutting-edge genetic engineering techniques and commitment to providing high-quality biological products tailored for the academic and pharmaceutical communities. Through our expertise, we aim to support impactful research and foster innovation in the understanding of complex genetic frameworks.
Please note that all services are for research use only. Not intended for any clinical use.
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