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RAB11FIP5 Knockout Cell Lines

Gene: RAB11FIP5

Official Full Name: RAB11 family interacting protein 5provided by HGNC

Gene Summary: Enables gamma-tubulin binding activity. Involved in cellular response to acidic pH; negative regulation of adiponectin secretion; and regulation of protein localization to cell surface. Located in centriolar satellite and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28395 RAB11FIP5 Knockout cell line (HeLa) Human RAB11FIP5 1:3~1:6 Negative Online Inquiry
KO28396 RAB11FIP5 Knockout cell line (HCT 116) Human RAB11FIP5 1:2~1:4 Negative Online Inquiry
KO28397 RAB11FIP5 Knockout cell line (HEK293) Human RAB11FIP5 1:3~1:6 Negative Online Inquiry
KO28398 RAB11FIP5 Knockout cell line (A549) Human RAB11FIP5 1:3~1:4 Negative Online Inquiry

Background

RAB11FIP5 Gene Knockout Cell Lines are specialized, genetically modified cell models that lack the RAB11FIP5 gene, which plays a crucial role in intracellular trafficking and endocytic recycling. These cell lines serve as invaluable tools for researchers studying the dynamics of vesicle transport and membrane trafficking processes, enabling a deeper understanding of cellular function and pathophysiological mechanisms associated with various diseases, including cancer and neurodegenerative disorders.

The RAB11FIP5 gene encodes a protein that interacts with the RAB11 family of GTPases, facilitating the recycling of vesicles back to the plasma membrane. By utilizing knockout models, researchers can analyze the effects of RAB11FIP5 loss on cellular processes such as cytokinesis, exocytosis, and endocytosis, providing insight into the molecular pathways that govern these essential functions. These cell lines can be employed in a wide array of applications ranging from drug discovery to the elucidation of disease mechanisms, making them highly relevant in both basic and translational research.

Compared to traditional cell lines, RAB11FIP5 Gene Knockout Cell Lines offer unique advantages including a clear, controlled genetic background that eliminates confounding variables inherent in wild-type models. Additionally, these lines have been validated for consistent results, ensuring reproducibility, which is crucial in scientific studies. Unlike other genetic modification techniques, the knockout approach allows for a comprehensive understanding of the gene's function through loss-of-function analysis, an invaluable asset in mechanistic studies.

For researchers and clinicians seeking to investigate the pathways impacted by RAB11FIP5, these knockout cell lines represent a critical resource. They enable the design of experiments that may lead to innovative therapeutic strategies targeting intracellular trafficking defects and associated diseases.

Our company is committed to advancing scientific research by offering high-quality biological products, including RAB11FIP5 Gene Knockout Cell Lines, backed by our expertise in genetic engineering and a dedication to supporting the scientific community. We ensure that our product offerings meet the highest standards of reliability and effectiveness, facilitating groundbreaking discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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