Gene: OSBPL10
Official Full Name: oxysterol binding protein like 10provided by HGNC
Gene Summary: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30707 | OSBPL10 Knockout cell line (HeLa) | Human | OSBPL10 | 1:3~1:6 | Negative | Online Inquiry |
KO30708 | OSBPL10 Knockout cell line (HCT 116) | Human | OSBPL10 | 1:2~1:4 | Negative | Online Inquiry |
KO30709 | OSBPL10 Knockout cell line (HEK293) | Human | OSBPL10 | 1:3~1:6 | Negative | Online Inquiry |
KO30710 | OSBPL10 Knockout cell line (A549) | Human | OSBPL10 | 1:3~1:4 | Negative | Online Inquiry |
OSBPL10 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the biological role of the OSBPL10 gene, which encodes a member of the oxysterol-binding protein-like family. These knockout cell lines are generated through targeted gene editing techniques, such as CRISPR-Cas9, effectively disrupting the expression of OSBPL10 and thereby enabling researchers to examine the resulting phenotypic effects. By eliminating the function of this gene, scientists can elucidate its involvement in cellular processes, such as lipid metabolism, endocytosis, and signaling pathways, which may impact disease states like cancer and metabolic disorders.
The primary function of the OSBPL10 gene is to bind specific lipids, influencing numerous cellular functions, including membrane trafficking and cytoplasmic signaling. By studying these gene knockout cell lines, researchers can gain insights into how OSBPL10 disruptions may impact cellular homeostasis and contribute to pathological conditions. In clinical settings, such models are invaluable for drug discovery and the identification of potential therapeutic targets, thereby accelerating translational research.
One significant advantage of using OSBPL10 Gene Knockout Cell Lines is the precision offered by CRISPR technology, which allows for specific, reproducible gene manipulation. This contrasts with traditional knockout methods, which may produce less controlled genomic changes and varied expressions. Additionally, these cell lines can be employed across a variety of experimental systems, making them versatile tools for comprehensive biological studies.
The value of OSBPL10 Gene Knockout Cell Lines to researchers and clinicians lies in their potential to advance our understanding of complex biological phenomena, thereby paving the way for novel interventions. Additionally, these tools contribute to the refinement of existing therapeutic approaches, potentially leading to improved patient outcomes.
With a commitment to excellence in biological research tools, our company employs state-of-the-art gene editing techniques and rigorous quality control measures to ensure that our OSBPL10 Gene Knockout Cell Lines meet the highest standards in scientific research.
Please note that all services are for research use only. Not intended for any clinical use.
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