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LAYN Knockout Cell Lines

Gene: LAYN

Official Full Name: layilinprovided by HGNC

Gene Summary: Enables hyaluronic acid binding activity. Located in focal adhesion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24148 LAYN Knockout cell line (A549) Human LAYN 1:3~1:4 Negative Online Inquiry

Background

LAYN Gene Knockout Cell Lines are specialized cellular models generated through targeted gene editing techniques, specifically designed to disable the expression of the LAYN (layilin) gene. These knockout cell lines serve as essential tools for investigating the physiological and pathological roles of LAYN, which has been implicated in various cellular processes including immune response modulation and tumorigenesis. By utilizing CRISPR-Cas9 or similar gene-editing technologies, each cell line has been engineered to eliminate LAYN expression, thereby allowing researchers to analyze the resultant phenotypic changes and their biological implications.

The primary mechanism by which LAYN Gene Knockout Cell Lines operate is through the complete absence of the LAYN protein, facilitating a deeper understanding of its functions in cellular adhesion, immune regulation, and metabolic pathways. By studying these knockout models, scientists can elucidate the pathways through which LAYN contributes to diseases such as cancer or autoimmune disorders, enhancing our knowledge base in molecular biology and immunology.

In research and clinical settings, these knockout cell lines are invaluable for drug discovery, functional genomics, and biomarker identification, representing a crucial step towards personalized medicine. Researchers can perform high-throughput screening for therapeutic interventions, assess the efficacy of novel compounds, and investigate the gene's role in treatment resistance.

One of the standout advantages of our LAYN Gene Knockout Cell Lines is their precision and reproducibility, which are often superior to traditional models. Unlike transient knockdown approaches, our knockout lines provide stable, long-term expression profiles, yielding more reliable data. Additionally, these cell lines are customizable and can be adapted for use with a variety of genetic backgrounds, making them versatile tools that cater to diverse research needs.

For researchers and clinicians seeking reliable and innovative solutions to advance their studies, LAYN Gene Knockout Cell Lines offer a robust platform for exploration and discovery in the realm of gene function and disease mechanisms. Our company brings decades of expertise in cellular biology and genetic engineering, ensuring that you have access to high-quality products along with comprehensive support for your scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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