Gene: KYAT3
Official Full Name: kynurenine aminotransferase 3provided by HGNC
Gene Summary: This gene encodes an aminotransferase that transaminates kynurenine to form kynurenic acid, which is a metabolite of tryptophan. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene. This gene shares 5' exon structure with the RNA binding motif protein, X-linked-like 1 locus on chromosome 1, but the coding sequences are non-overlapping. [provided by RefSeq, Mar 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16613 | KYAT3 Knockout cell line (HeLa) | Human | KYAT3 | 1:3~1:6 | Negative | Online Inquiry |
KO16614 | KYAT3 Knockout cell line (HCT 116) | Human | KYAT3 | 1:2~1:4 | Negative | Online Inquiry |
KO16615 | KYAT3 Knockout cell line (HEK293) | Human | KYAT3 | 1:3~1:6 | Negative | Online Inquiry |
KO16616 | KYAT3 Knockout cell line (A549) | Human | KYAT3 | 1:3~1:4 | Negative | Online Inquiry |
KYAT3 Gene Knockout Cell Lines are genetically modified cell cultures engineered to lack the expression of the KYAT3 gene, which encodes for the enzyme Kynurenine Aminotransferase 3. These cell lines play a critical role in the study of various biological processes, particularly in understanding metabolism related to the kynurenine pathway, which has implications in neurobiology, immunology, and cancer research. By precisely knocking out the KYAT3 gene, researchers can investigate the physiological roles of Kynurenine Aminotransferase 3, examining how its absence affects cellular metabolism, signaling pathways, and cellular responses to stress.
The function of these knockout cell lines primarily lies in their utility for elucidating the pathways regulated by kynurenine and its metabolites. Researchers can explore how KYAT3 modulation influences neurotransmitter levels, immune responses, and tumor microenvironments. By utilizing these cell lines, scientists gain insights into the molecular mechanisms underlying diseases such as depression, neurodegenerative disorders, and various cancers, leading to the identification of potential therapeutic targets.
Compared to traditional methods of gene silencing, such as RNA interference, KYAT3 Gene Knockout Cell Lines offer a more stable and permanent solution for studying gene function, enabling reproducible results in long-term experiments. Furthermore, these cell lines are designed to streamline experimental procedures, facilitating high-throughput screening for drug discovery and robust experimental analytics.
The scientific importance of KYAT3 Gene Knockout Cell Lines cannot be overstated, as they provide a unique toolset for researchers and clinicians who aim to dissect complex biological questions related to the kynurenine pathway and its impact on human health. Their specific advantages, combined with robust experimental platforms, make these cell lines a vital resource in advancing our understanding of disease mechanisms.
Our company prides itself on a strong foundation in genetic engineering and cell biology, ensuring that our products meet the highest standards of quality and innovation. We are committed to empowering researchers and healthcare professionals by providing tools that advance scientific discovery and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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