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KCTD21 Knockout Cell Lines

Gene: KCTD21

Official Full Name: potassium channel tetramerization domain containing 21provided by HGNC

Gene Summary: Enables cullin family protein binding activity; histone deacetylase binding activity; and identical protein binding activity. Involved in negative regulation of smoothened signaling pathway and ubiquitin-dependent protein catabolic process. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16796 KCTD21 Knockout cell line (HeLa) Human KCTD21 1:3~1:6 Negative Online Inquiry
KO16797 KCTD21 Knockout cell line (HCT 116) Human KCTD21 1:2~1:4 Negative Online Inquiry
KO16798 KCTD21 Knockout cell line (HEK293) Human KCTD21 1:3~1:6 Negative Online Inquiry
KO16799 KCTD21 Knockout cell line (A549) Human KCTD21 1:3~1:4 Negative Online Inquiry

Background

KCTD21 Gene Knockout Cell Lines are genetically modified cell lines engineered to lack the KCTD21 gene, offering researchers a powerful tool for investigating its role in various biological processes and diseases. These knockout cell lines utilize CRISPR-Cas9 technology, a precise and efficient method for gene editing, to disrupt the function of KCTD21 without significantly altering surrounding gene expression. This mechanism enables the study of gene function and its associated pathways in a controlled environment, providing insight into the gene’s involvement in neurodevelopmental disorders and other pathologies.

The scientific importance of KCTD21 Gene Knockout Cell Lines lies in their ability to facilitate research into the gene's function and its implications in various cellular processes, including cell proliferation, differentiation, and signaling pathways. Their applications are particularly valuable in fields such as molecular biology, genetics, and pharmacology, where understanding the consequences of gene loss can aid in drug development and therapeutic interventions.

Compared to traditional knockdown methods like RNA interference, KCTD21 Gene Knockout Cell Lines offer a permanent solution, allowing for the comprehensive assessment of long-term gene effects. Additionally, the use of CRISPR-Cas9 leads to a more robust and reliable knockout, providing more consistent results for experimental reproducibility.

For researchers and clinicians aiming to elucidate the mechanisms underlying disease, KCTD21 Gene Knockout Cell Lines represent a foundational asset in their research toolkit. The capacity to investigate gene function with precision and depth positions these cell lines as an invaluable resource for advancing biomedical knowledge and developing targeted treatments.

Our company specializes in cutting-edge genetic tools and cell line development, ensuring that our products meet the highest standards of quality and efficacy. With a commitment to empowering scientific discovery, we provide innovative solutions that support the advancement of research across diverse fields.

Please note that all services are for research use only. Not intended for any clinical use.

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