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IRX3 Knockout Cell Lines

Gene: IRX3

Official Full Name: iroquois homeobox 3provided by HGNC

Gene Summary: IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16883 IRX3 Knockout cell line (HeLa) Human IRX3 1:3~1:6 Negative Online Inquiry
KO16884 IRX3 Knockout cell line (HEK293) Human IRX3 1:3~1:6 Negative Online Inquiry

Background

IRX3 Gene Knockout Cell Lines are a sophisticated toolkit for genetic research that enables scientists to investigate the role of the IRX3 gene in various biological processes. These cell lines have been specifically engineered using CRISPR/Cas9 technology to introduce targeted disruptions in the IRX3 gene, which is known to be implicated in the regulation of cellular differentiation, metabolism, and neural development.

The primary function of these knockout cell lines is to facilitate the study of IRX3-associated pathways, providing researchers with insights into its contributions to health and disease. By comparing the phenotypic and molecular characteristics of wild-type cells with these knockout variants, scientists can elucidate the gene's functional roles in diverse contexts, such as obesity, diabetes, and neurodevelopmental disorders. The precise mechanism of action involves the loss of IRX3 expression, allowing for the exploration of compensatory pathways and gene interactions.

The scientific significance of IRX3 Gene Knockout Cell Lines extends into both research and clinical applications. In basic research, these models pave the way for understanding the genetic basis of complex traits and diseases. Clinically, they offer a platform for developing therapeutic strategies aimed at targeting IRX3-related disorders, including drug discovery and personalized medicine initiatives.

One of the distinguishing advantages of our IRX3 Gene Knockout Cell Lines is their high specificity and efficiency, minimizing off-target effects commonly associated with genetic modifications. This precision, coupled with a robust validation process, ensures reliable and reproducible results, making these cell lines invaluable in comparative studies. Furthermore, our production methods prioritize quality control, allowing for consistent cell line performance across multiple experiments.

For researchers, clinicians, and biopharmaceutical companies seeking to deepen their understanding of genetic determinants of health, IRX3 Gene Knockout Cell Lines present a powerful and versatile tool. The potential applications span from translational research to therapeutic development, empowering users to advance their scientific inquiries and treatment methodologies.

Our company's expertise in genetic engineering and commitment to providing high-quality biological products enable us to meet the needs of the scientific community effectively. With a focus on innovation and customer support, we aim to help researchers unlock new biological insights through our exceptional product offerings.

Please note that all services are for research use only. Not intended for any clinical use.

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