Gene: HOXB9
Official Full Name: homeobox B9provided by HGNC
Gene Summary: This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37245 | HOXB9 Knockout cell line (HeLa) | Human | HOXB9 | 1:3~1:6 | Negative | Online Inquiry |
KO37246 | HOXB9 Knockout cell line (HCT 116) | Human | HOXB9 | 1:2~1:4 | Negative | Online Inquiry |
KO37247 | HOXB9 Knockout cell line (HEK293) | Human | HOXB9 | 1:3~1:6 | Negative | Online Inquiry |
KO37248 | HOXB9 Knockout cell line (A549) | Human | HOXB9 | 1:3~1:4 | Negative | Online Inquiry |
HOXB9 Gene Knockout Cell Lines are specialized cellular models engineered to provide researchers with a vital tool for investigating the functional roles of the HOXB9 gene. HOXB9 is part of the homeobox gene family, which plays a crucial role in developmental processes and gene regulation during embryogenesis. By creating knockout cell lines, where the HOXB9 gene is selectively disrupted, researchers can study the downstream effects of its absence on cellular behavior, signaling pathways, and gene expression profiles.
These cell lines are indispensable for understanding the mechanisms by which HOXB9 influences stem cell differentiation, oncogenesis, and other pathophysiological conditions. Utilizing CRISPR-Cas9 gene-editing technology, the knockout process ensures precision, allowing for the exploration of phenotype changes, alterations in developmental pathways, and the identification of potential biomarkers for diseases. This method not only assures a high efficiency in gene disruption but also minimizes off-target effects, which are crucial for obtaining reliable results in experiments.
The scientific importance of HOXB9 Gene Knockout Cell Lines spans various applications, from basic research in genetics and development to more applied clinical research, particularly in cancer biology. By elucidating the role of HOXB9 in tumor progression or stem cell maintenance, scientists can identify new therapeutic targets and develop strategies for intervention.
When comparing HOXB9 Gene Knockout Cell Lines to alternative models, their specificity and the reliability of results set them apart. While traditional methods may involve pharmacological inhibition or transgenic models with systemic effects, using these knockout lines allows for focused studies that can accelerate insights into HOXB9's role.
For researchers and clinicians aiming to delve into gene function or develop novel therapies, HOXB9 Gene Knockout Cell Lines offer a robust platform. They not only streamline research efforts but also hold the potential to translate findings into clinical applications, enhancing our understanding of gene regulation and its implications in health and disease.
Our company, a leader in providing advanced biological models, is committed to supporting the scientific community with high-quality products like HOXB9 Gene Knockout Cell Lines. Our expertise in genetic engineering and commitment to innovation ensures that researchers have access to the best tools for their cutting-edge studies.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.