Home / H3C1 Knockout Cell Lines

H3C1 Knockout Cell Lines

Gene: H3C1

Official Full Name: H3 clustered histone 1provided by HGNC

Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34247 H3C1 Knockout cell line (HeLa) Human H3C1 1:3~1:6 Negative Online Inquiry
KO34248 H3C1 Knockout cell line (HCT 116) Human H3C1 1:2~1:4 Negative Online Inquiry
KO34249 H3C1 Knockout cell line (HEK293) Human H3C1 1:3~1:6 Negative Online Inquiry

Background

H3C1 Gene Knockout Cell Lines are advanced, genetically modified cellular models designed to facilitate the in-depth study of the H3C1 gene's biological functions and its role in various cellular processes. These knockout cell lines are engineered to specifically disable the H3C1 gene, enabling researchers to explore the consequences of its absence and to elucidate its contribution to key pathways such as gene regulation, cellular metabolism, and signal transduction.

The primary function of H3C1 Gene Knockout Cell Lines lies in their ability to mimic certain disease states by providing a platform for functional genomics and pharmacological screening. By having a specific gene removed, researchers can investigate compensatory mechanisms and identify novel therapeutic targets. This is accomplished through comprehensive assays that measure alterations in cell growth, differentiation, apoptosis, and response to external stimuli.

The scientific importance of H3C1 Gene Knockout Cell Lines cannot be overstated; they serve as invaluable tools in translational research, particularly in the fields of cancer biology, neurobiology, and developmental studies. By analyzing these cells, scientists can derive insights into gene function and molecular interactions, ultimately leading to advancements in personalized medicine and targeted therapies.

H3C1 Gene Knockout Cell Lines offer several advantages over existing alternatives, such as transient knockdown methods, which often result in incomplete and temporary suppression of target gene expression. The knockout approach provides a stable and robust model, ensuring reproducibility in experimental outcomes, which is crucial for rigorous scientific inquiry.

For researchers and clinicians seeking to enhance their understanding of gene function and its implications in disease, H3C1 Gene Knockout Cell Lines represent a transformative resource. With these cell lines, scientific inquiries become more definitive, paving the way for breakthroughs in therapeutic strategies and improved patient outcomes.

Our company prides itself on its expertise in custom cell line development and biotechnological innovation, leading the field with cutting-edge solutions that empower researchers in their quest to unravel the complexities of biology. We ensure high-quality products that facilitate advancements in scientific discovery and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.