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FST Knockout Cell Lines

Gene: FST

Official Full Name: follistatinprovided by HGNC

Gene Summary: Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11553 FST Knockout cell line (HeLa) Human FST 1:3~1:6 Negative Online Inquiry
KO11554 FST Knockout cell line (A549) Human FST 1:3~1:4 Negative Online Inquiry

Background

FST Gene Knockout Cell Lines are genetically engineered cell lines in which the FST gene has been deliberately disrupted, allowing for the study of its role in biological processes such as cell signaling, metabolism, and development. These knockout models serve as invaluable tools in elucidating the functional consequences of FST gene loss, which is particularly important in understanding various physiological and pathological conditions, including cancer and metabolic disorders.

The mechanism of action of the FST Gene Knockout Cell Lines is rooted in the targeted CRISPR/Cas9 technology used to achieve gene disruption. This approach enables precise editing of the genomic sequence, allowing researchers to study the resultant phenotypic changes and alterations in cellular pathways influenced by FST. By providing a controlled experimental system, these knockout cell lines facilitate high-throughput screening and allow for the exploration of potential therapeutic targets related to FST regulation.

The scientific importance of FST Gene Knockout Cell Lines extends to both research and clinical applications, as they enable researchers to model diseases more accurately and to develop targeted therapies. The established link between FST and various biological processes underscores the need for such models in drug discovery and basic research, offering insights that may lead to innovative therapeutic strategies.

Advantages of FST Gene Knockout Cell Lines over traditional cell models include their enhanced specificity, reproducibility, and the ability to conduct functional assays with high sensitivity. Unlike non-targeted models, which may exhibit variable expression levels, these knockout lines provide a consistent baseline for experimental analysis, ensuring reliability in results.

For researchers and clinicians alike, the value of FST Gene Knockout Cell Lines lies in their potential to accelerate the understanding of gene function and its implications in health and disease. By utilizing these specialized cell lines, users can make groundbreaking discoveries that translate into clinical advancements.

Our company, renowned for its commitment to excellence in genetic engineering and cell line development, offers a diverse portfolio of genetically modified cell lines, including the FST Gene Knockout Cell Lines, ensuring researchers have access to cutting-edge tools for their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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