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ENO3 Knockout Cell Lines

Gene: ENO3

Official Full Name: enolase 3provided by HGNC

Gene Summary: This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08241 ENO3 Knockout cell line (HeLa) Human ENO3 1:3~1:6 Negative Online Inquiry
KO08242 ENO3 Knockout cell line (HCT 116) Human ENO3 1:2~1:4 Negative Online Inquiry
KO08243 ENO3 Knockout cell line (HEK293) Human ENO3 1:3~1:6 Negative Online Inquiry
KO08244 ENO3 Knockout cell line (A549) Human ENO3 1:3~1:4 Negative Online Inquiry

Background

ENO3 Gene Knockout Cell Lines are specialized cellular models engineered to specifically lack the expression of the ENO3 gene, which encodes the enzyme enolase 3, a crucial component in the glycolytic pathway. By knocking out this gene, researchers can investigate the role of ENO3 in various cellular processes, especially in metabolism and energy production. This targeted genetic alteration enables the examination of how dysregulation of the glycolytic pathway can contribute to diseases such as cancer and muscular dystrophy.

The key functions of ENO3 Gene Knockout Cell Lines include enabling in-depth studies of metabolic changes, cell growth, and apoptosis in a controlled environment. These cell lines provide insights into alternative metabolic pathways that may be activated when ENO3 is absent, thereby elucidating compensatory mechanisms that could be potential targets for therapy. The unique capability of these lines to mimic pathological states offers substantial advantages for researchers focused on metabolic diseases and cancer biology.

The scientific importance of these knockout cell lines extends to both fundamental research and translational applications. They serve as invaluable tools for drug screening, allowing for the evaluation of therapeutic compounds that may target glycolysis-related pathways. Additionally, researchers can utilize these models to better understand the implications of ENO3 deficiency in specific disorders, thus bridging the gap between basic science and clinical therapeutics.

What sets ENO3 Gene Knockout Cell Lines apart from traditional cell models is their specificity in gene targeting and the robustness of their phenotypic responses. Unlike conventional cell lines, these models provide more accurate representations of conditions lacking ENO3, making them critical for obtaining reliable, reproducible data. The added precision allows researchers to develop more effective experimental protocols, enhancing the overall quality of their findings.

Our company specializes in producing high-quality biological products with a strong emphasis on genetic engineering. With expertise in advanced cell line development, we are committed to supporting the scientific community with tools that drive innovation and promote breakthroughs in research and therapy. Selecting ENO3 Gene Knockout Cell Lines means investing in a scientifically sound, high-efficiency model that will facilitate your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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