Gene: DHRS1
Official Full Name: dehydrogenase/reductase 1provided by HGNC
Gene Summary: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30582 | DHRS1 Knockout cell line (HeLa) | Human | DHRS1 | 1:3~1:6 | Negative | Online Inquiry |
KO30583 | DHRS1 Knockout cell line (HCT 116) | Human | DHRS1 | 1:2~1:4 | Negative | Online Inquiry |
KO30584 | DHRS1 Knockout cell line (HEK293) | Human | DHRS1 | 1:3~1:6 | Negative | Online Inquiry |
KO30585 | DHRS1 Knockout cell line (A549) | Human | DHRS1 | 1:3~1:4 | Negative | Online Inquiry |
DHRS1 Gene Knockout Cell Lines are specialized cellular models engineered to specifically eliminate the expression of the DHRS1 gene, which encodes for an enzyme involved in steroid metabolism and redox reactions. These cell lines are pivotal for studying the functional implications of DHRS1 deficiency and its role in various biological pathways, particularly in metabolic regulation and pathophysiological contexts such as cancer and cardiovascular diseases.
The primary mechanism through which these knockout cell lines operate is through CRISPR-Cas9 gene editing technology, enabling precise ablation of the DHRS1 gene. This results in the loss of gene function, allowing researchers to investigate the cellular and molecular consequences of DHRS1 absence. By employing these knockout models, scientists can dissect complex regulatory networks, elucidate metabolic flux, and identify potential therapeutic targets.
The scientific importance of DHRS1 Gene Knockout Cell Lines cannot be overstated, as they provide a vital tool for understanding the gene's involvement in critical biological processes and disease mechanisms. In clinical research settings, these models facilitate drug screening and the evaluation of new therapeutic interventions aimed at restoring normal function in DHRS1-related disorders.
A significant advantage of using DHRS1 Gene Knockout Cell Lines over traditional models is the precision and specificity afforded by the CRISPR-Cas9 technology, which minimizes off-target effects. Additionally, these cell lines are equipped with robust validation protocols, ensuring data reliability. They offer a unique platform that can be tailored for various applications, such as high-throughput screening and functional genomics.
In an era where the intricacies of molecular biology are at the forefront of therapeutic development, the value of DHRS1 Gene Knockout Cell Lines to researchers and clinicians is paramount. They empower users to derive insights that could lead to novel treatment strategies and improve understanding of disease mechanisms.
Our company boasts a strong reputation in the field of genetic engineering and cell line development, delivering high-quality products that meet the rigorous standards of scientific research and biotechnology applications. With our expertise, we are committed to supporting your research with cutting-edge tools like DHRS1 Gene Knockout Cell Lines.
Please note that all services are for research use only. Not intended for any clinical use.
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