Gene: DAPL1
Official Full Name: death associated protein like 1provided by HGNC
Gene Summary: Predicted to enable ribosome binding activity; translation initiation factor binding activity; and translation repressor activity. Predicted to be involved in several processes, including cellular response to amino acid starvation; negative regulation of CD8-positive, alpha-beta T cell activation; and negative regulation of metabolic process. Predicted to act upstream of or within cell population proliferation and gene expression. Predicted to be located in membrane. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23239 | DAPL1 Knockout cell line (HeLa) | Human | DAPL1 | 1:3~1:6 | Negative | Online Inquiry |
DAPL1 Gene Knockout Cell Lines are genetically engineered cell lines that have had the DAPL1 gene specifically disrupted or inactivated. This product enables researchers to investigate the biological functions and pathways mediated by the DAPL1 protein, which is implicated in various cellular processes, including cytoskeletal dynamics and cell signaling. By utilizing these knockout cell lines, scientists can elucidate the role of DAPL1 in physiological and pathophysiological contexts, particularly in studies related to cancer, neurodegeneration, and cell migration.
The key mechanism by which DAPL1 knockout cell lines operate revolves around the complete lack of functional DAPL1 protein expression, leading to observable phenotypic changes. This allows for rigorous examination of the molecular pathways affected by the absence of DAPL1, thus providing insights into its contributions to critical cellular functions. As a result, researchers can better understand how perturbations in this gene may lead to disease, paving the way for potential therapeutic interventions.
The scientific significance of DAPL1 gene knockout cell lines extends beyond basic research; these models have substantial applications in drug discovery and development. By assessing the cellular response to various compounds in the absence of DAPL1, scientists can identify novel targets for therapeutic exploitation and evaluate the efficacy of drug candidates more accurately.
What sets DAPL1 Gene Knockout Cell Lines apart from alternative models is their high specificity and versatility. While other knockout models may have off-target effects or lack adequate characterization, these cell lines are rigorously validated for DAPL1 mutation and exhibit consistent expression levels. This ensures that experimental results are reliable and reproducible, providing enhanced confidence in research findings.
For researchers and clinicians, the value of DAPL1 Gene Knockout Cell Lines lies not only in their capacity for elucidating the biological impact of the DAPL1 gene but also in their potential to foster novel therapeutic strategies. The insights gained from using these cell lines can lead to breakthroughs in understanding diseases tied to DAPL1 dysfunction, ultimately contributing to advancements in medical science.
Our company specializes in providing high-quality biological products, leveraging state-of-the-art gene editing technologies and rigorous validation processes. Our expertise in developing customized and ready-to-use genetic models is at the forefront of innovation, empowering researchers to achieve their scientific goals with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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