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CLUL1 Knockout Cell Lines

Gene: CLUL1

Official Full Name: clusterin like 1provided by HGNC

Gene Summary: Predicted to enable misfolded protein binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27842 CLUL1 Knockout cell line (HEK293) Human CLUL1 1:3~1:6 Negative Online Inquiry

Background

CLUL1 Gene Knockout Cell Lines are specialized cell lines in which the CLUL1 gene has been precisely disrupted, allowing for the study of its biological functions and contributions to cellular processes. These knockout cell lines serve as indispensable tools for researchers investigating the role of CLUL1 in various tissue contexts, cellular signaling pathways, and disease mechanisms, particularly those related to neurological disorders.

The key mechanism through which CLUL1 knockout cell lines operate involves the deletion of the CLUL1 gene, leading to a complete loss of its corresponding protein. This functional loss enables scientists to explore the cellular compensatory mechanisms and interactions that occur in response to the absence of the CLUL1 protein, thereby elucidating its significance in protein synthesis, cellular stress responses, and metabolic regulation. By utilizing these knockout models, researchers can conduct targeted experiments to dissect the gene's role in inflammation, immune responses, and other critical biological functions.

The scientific importance of CLUL1 Gene Knockout Cell Lines lies in their ability to promote advancements in both basic and applied research. These cell lines can be employed in pharmacological studies to evaluate drug efficacy and toxicity, contributing to the development of novel therapeutics. Clinically, understanding the implications of CLUL1 loss can deepen insights into conditions such as neurodegenerative diseases, where alterations in gene expression may lead to pathophysiological changes.

One of the main advantages of our CLUL1 Gene Knockout Cell Lines is their rigorous validation, providing confidence in their genetic modification and phenotypic consistency. Unlike other alternatives that may feature partial gene knockdowns or non-specific mutations, our cell lines assure complete ablation of the CLUL1 function, offering a more robust platform for experimental reproducibility and accuracy. Additionally, they come with a detailed characterisation report, facilitating straightforward integration into existing research frameworks.

These cell lines represent a valuable asset for researchers and clinicians alike, as they enable the dissection of complex biological questions with precision. By using our CLUL1 Gene Knockout Cell Lines, users can enhance the quality of their findings and ultimately propel their research forward in the search for innovative therapies.

With a commitment to excellence in biological research tools, our company is dedicated to providing high-quality, reliable products that empower scientific discovery and innovation. Our expertise in gene editing and cell line development ensures that customers receive products tailored to their research needs, backed by exceptional support from our knowledgeable team.

Please note that all services are for research use only. Not intended for any clinical use.

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