Gene: CHIC2
Official Full Name: cysteine rich hydrophobic domain 2provided by HGNC
Gene Summary: This gene encodes a member of the CHIC family of proteins. The encoded protein contains a cysteine-rich hydrophobic (CHIC) motif, and is localized to vesicular structures and the plasma membrane. This gene is associated with some cases of acute myeloid leukemia. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28081 | CHIC2 Knockout cell line (HeLa) | Human | CHIC2 | 1:3~1:6 | Negative | Online Inquiry |
KO28082 | CHIC2 Knockout cell line (HCT 116) | Human | CHIC2 | 1:2~1:4 | Negative | Online Inquiry |
KO28083 | CHIC2 Knockout cell line (HEK293) | Human | CHIC2 | 1:3~1:6 | Negative | Online Inquiry |
KO28084 | CHIC2 Knockout cell line (A549) | Human | CHIC2 | 1:3~1:4 | Negative | Online Inquiry |
CHIC2 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the role of the CHIC2 gene in various biological processes. Utilizing advanced CRISPR-Cas9 technology, these cell lines exhibit a complete disruption of the CHIC2 gene, allowing researchers to investigate its functions in cellular mechanisms such as signal transduction, cell proliferation, and apoptosis. This knockout strategy is pivotal for elucidating the gene's contributions to both normal physiology and disease states, particularly in pathology related to cellular responses and modulation.
The key functions and mechanisms of CHIC2 Gene Knockout Cell Lines are centered around their ability to illustrate the biological impact of the absence of the CHIC2 gene. Researchers can employ these cell lines to delve into downstream signaling pathways, analyze gene expression profiles, and explore how CHIC2 interacts with other molecular players in the cell. By removing this gene, scientists can gain insights into compensatory mechanisms employed by the cell and assess the possible therapeutic avenues for diseases where CHIC2 is implicated.
The scientific importance of these cell lines cannot be overstated, particularly in cancer research, developmental biology, and neurobiology. CHIC2 is linked to crucial processes in cancer progression, immune response, and neuronal function; hence, the knockout cell lines serve as invaluable tools in understanding these complex pathways, facilitating drug development, and identifying novel therapeutic targets in clinical settings.
In comparison to traditional methods of gene silencing, such as siRNA or shRNA approaches, CHIC2 Gene Knockout Cell Lines offer the advantage of a stable genetic modification, ensuring consistent results across experiments. Furthermore, they eliminate off-target effects often associated with transient knockdown techniques, thus providing researchers with reliable, robust data.
These cell lines are invaluable to researchers and clinicians by providing a reliable foundation for experimental reproducibility, allowing for precise modulation of gene function without the confounding variables inherent in other methods. Moreover, understanding the CHIC2 gene’s function can lead to advancements in personalized medicine and innovative treatment strategies for diseases where its roles are critical.
As a leader in the development of advanced biological products, our company leverages cutting-edge technology, extensive research experience, and a commitment to quality, ensuring that our CHIC2 Gene Knockout Cell Lines meet the highest standards of scientific integrity and utility in your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.