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ARPC5 Knockout Cell Lines

Gene: ARPC5

Official Full Name: actin related protein 2/3 complex subunit 5provided by HGNC

Gene Summary: This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32299 ARPC5 Knockout cell line (HeLa) Human ARPC5 1:3~1:6 Negative Online Inquiry
KO32300 ARPC5 Knockout cell line (HCT 116) Human ARPC5 1:2~1:4 Negative Online Inquiry
KO32301 ARPC5 Knockout cell line (HEK293) Human ARPC5 1:3~1:6 Negative Online Inquiry
KO32302 ARPC5 Knockout cell line (A549) Human ARPC5 1:3~1:4 Negative Online Inquiry

Background

ARPC5 Gene Knockout Cell Lines are a specialized collection of mammalian cell lines in which the ARPC5 gene has been rendered non-functional through targeted genomic modifications. The ARPC5 gene encodes a subunit of the Arp2/3 complex, which plays a critical role in regulating actin dynamics, facilitating cellular processes such as migration, division, and the formation of cellular structures. By utilizing CRISPR-Cas9 or similar gene-editing technologies, these knockout cell lines serve as invaluable tools for researchers aiming to dissect the downstream signaling pathways and cellular mechanisms influenced by ARPC5.

The primary function of ARPC5 Gene Knockout Cell Lines is to enable the study of actin-related processes and their implications in various biological phenomena, including cancer metastasis and immune responses. By observing the effects of the absence of ARPC5, scientists can better understand the molecular interactions and changes that occur when actin polymerization is disrupted. These insights have significant implications in drug development and therapeutic interventions aimed at modulating actin dynamics in diseases characterized by aberrant cell movement and growth.

What sets our ARPC5 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, ensuring consistent results that are crucial for experimental validity. Additionally, these cell lines are derived from commonly used model organisms, enabling seamless integration into existing workflows in both research and clinical laboratories.

For researchers and clinicians focused on advancing therapies that target cellular mechanics or studying actin-related disorders, these cell lines offer a strategic advantage by providing a focused approach to understanding ARPC5's role without the confounding factors present in wild-type models. The ability to elucidate the function of ARPC5 in real-time paves the way for the development of novel strategies for cancer treatment and regenerative medicine.

As an industry leader in biotechnology, our company prides itself on delivering high-quality, validated genetic models and cell lines that address critical areas of biological research. By choosing our ARPC5 Gene Knockout Cell Lines, you are equipping your lab with state-of-the-art tools designed to empower groundbreaking discoveries in cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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