Gene: ADNP2
Official Full Name: ADNP homeobox 2provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in nervous system development and regulation of gene expression. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30258 | ADNP2 Knockout cell line (HeLa) | Human | ADNP2 | 1:3~1:6 | Negative | Online Inquiry |
KO30259 | ADNP2 Knockout cell line (HCT 116) | Human | ADNP2 | 1:2~1:4 | Negative | Online Inquiry |
KO30260 | ADNP2 Knockout cell line (HEK293) | Human | ADNP2 | 1:3~1:6 | Negative | Online Inquiry |
KO30261 | ADNP2 Knockout cell line (A549) | Human | ADNP2 | 1:3~1:4 | Negative | Online Inquiry |
ADNP2 Gene Knockout Cell Lines are genetically modified cellular models in which the ADNP2 gene has been intentionally disrupted to study the gene's function and its role in various biological processes. The ADNP2 gene encodes for a critical neuronal protein that is implicated in neurodevelopmental pathways. By utilizing these knockout cell lines, researchers can pinpoint the effects of ADNP2 loss on cellular behavior, signaling pathways, and gene expression associated with neurogenesis and cognitive functions.
The key function of ADNP2 Gene Knockout Cell Lines lies in their ability to provide insights into the molecular mechanisms governed by ADNP2, making them particularly valuable for understanding neurodevelopmental disorders, including autism spectrum disorders and intellectual disabilities. This cellular model facilitates experimentation by allowing researchers to compare knockout cells against wild-type counterparts, thereby elucidating the consequences of ADNP2 deficiency on cellular proliferation, differentiation, and synaptic activity.
In terms of scientific importance, these cell lines serve as an indispensable tool in both basic research and clinical settings, enabling advanced studies that could lead to novel therapeutic targets for neurodevelopmental pathologies. Their use can significantly streamline drug discovery processes by providing a reliable platform to test potential compounds aimed at restoring normal cellular functions affected by ADNP2 disruptions.
Compared to alternative models such as RNA interference or pharmacological inhibition, ADNP2 Gene Knockout Cell Lines offer a more stable and permanent approach to studying the gene's role, ensuring consistency across experiments. The elimination of compensatory pathways observed in transient approaches further enhances data accuracy and reproducibility.
For researchers and clinicians dedicated to advancing our understanding of neurodevelopmental disorders, the ADNP2 Gene Knockout Cell Lines represent a critical asset. The ability to conduct targeted studies with precise genetic control fosters innovative research directions and promotes breakthroughs in therapeutic development.
Our company specializes in the production of high-quality genetic models tailored for cutting-edge research. With a commitment to scientific excellence, we provide robust tools that enable researchers to advance their studies and contribute significantly to the field of neurobiology.
Please note that all services are for research use only. Not intended for any clinical use.
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