Home / ABTB3 Knockout Cell Lines

ABTB3 Knockout Cell Lines

Gene: ABTB3

Official Full Name: ankyrin repeat and BTB domain containing 3provided by HGNC

Gene Summary: Predicted to enable PDZ domain binding activity and protein heterodimerization activity. Predicted to act upstream of or within exploration behavior; glutamatergic synaptic transmission; and protein stabilization. Predicted to be located in glutamatergic synapse and membrane. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20064 ABTB3 Knockout cell line (HCT 116) Human ABTB3 1:2~1:4 Negative Online Inquiry
KO20065 ABTB3 Knockout cell line (HEK293) Human ABTB3 1:3~1:6 Negative Online Inquiry
KO20066 ABTB3 Knockout cell line (A549) Human ABTB3 1:3~1:4 Negative Online Inquiry

Background

ABTB3 Gene Knockout Cell Lines are genetically engineered cell lines that have had the ABTB3 gene inactivated, allowing researchers to specifically investigate the biological roles and pathways associated with this gene. The ABTB3 gene is involved in various cellular processes, including the regulation of protein degradation and cell signaling pathways, making its study crucial for understanding disease mechanisms, particularly in cancer and neurodegenerative disorders.

These knockout cell lines function by utilizing CRISPR-Cas9 technology, which facilitates precise gene editing through the introduction of targeted double-strand breaks in the DNA. As a result, researchers can observe the phenotypic and molecular changes that occur in the absence of the ABTB3 gene. This allows for in-depth studies regarding cellular behavior, gene interactions, and the downstream effects on cellular functionality.

In both research and clinical applications, ABTB3 Gene Knockout Cell Lines are invaluable for elucidating mechanistic insights into disease pathology, drug response, and therapeutic strategies. Their utility extends to high-throughput screening for novel therapeutics, as they provide a defined genetic background that is essential for reproducible and reliable data.

The unique advantage of utilizing ABTB3 Gene Knockout Cell Lines over other alternatives lies in their specificity and reliability. Unlike conventional methods that may involve transient gene silencing or overexpression, these knockout cell lines offer stable expression profiles, ensuring consistency in experimental outcomes. This leads to more robust data that can significantly improve research efficiency and accuracy.

For researchers and clinicians seeking to deepen their understanding of the ABTB3 gene's role in health and disease, these knockout cell lines represent a powerful tool. By leveraging our advanced expertise in genetic engineering and cell biology, our company is committed to providing high-quality biological products that drive scientific discovery and innovation, enabling you to unlock new potentials in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.