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STK36 Knockout cell line (HeLa)

Catalog Number: KO06915

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Specifications

Product Information
Product Name STK36 Knockout cell line (HeLa)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:6
species Human
Gene STK36
Gene ID 27148
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%DMEM+10% FBS
Parental Cell Line HeLa
Quality Control Genotype: STK36 Knockout cell line (HeLa) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name serine/threonine kinase 36provided by HGNC
Also known as FU; CILD46
Gene Description This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Expression Broad expression in testis (RPKM 24.8), gall bladder (RPKM 6.4) and 21 other tissues See more

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