Gene: STK36
Official Full Name: serine/threonine kinase 36provided by HGNC
Gene Summary: This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06915 | STK36 Knockout cell line (HeLa) | Human | STK36 | 1:3~1:6 | Negative | Online Inquiry |
KO06916 | STK36 Knockout cell line (HCT 116) | Human | STK36 | 1:2~1:4 | Negative | Online Inquiry |
KO06917 | STK36 Knockout cell line (HEK293) | Human | STK36 | 1:3~1:6 | Negative | Online Inquiry |
KO06918 | STK36 Knockout cell line (A549) | Human | STK36 | 1:3~1:4 | Negative | Online Inquiry |
STK36 Gene Knockout Cell Lines are precisely engineered cellular models that facilitate the study of the STK36 gene, known to influence numerous cellular processes including proliferation, differentiation, and response to stress. These cell lines have been developed using advanced CRISPR-Cas9 genome editing technology, ensuring complete knockout of STK36 expression, thereby allowing researchers to analyze the resulting phenotypic and functional changes with high specificity.
The key function of the STK36 Gene Knockout Cell Lines lies in their ability to provide insights into the role of STK36 in various biological pathways. Researchers can investigate the implications of STK36 absence on cell cycle regulation and signal transduction pathways, contributing to a deeper understanding of its potential involvement in diseases such as cancer or developmental disorders. This cellular model is crucial in elucidating the mechanistic underpinnings of STK36, paving the way for targeted therapeutic strategies.
The availability of STK36 Gene Knockout Cell Lines is of significant scientific importance. In clinical research and drug development settings, these models can be used to assess the efficacy of novel compounds aimed at modulating STK36-related pathways, ultimately aiding in the advancement of targeted therapies. Moreover, they are vital for academic researchers seeking to explore novel hypotheses related to gene function and regulation.
One distinctive advantage of our STK36 Gene Knockout Cell Lines is their validated knockout efficiency and consistency across batches, owing to our rigorous quality control processes. Unlike other cell lines that may have inconsistent gene expression profiles, our models guarantee reliable reproducibility, which is critical in ensuring the validity of experimental results. Furthermore, these cell lines come with comprehensive documentation, including detailed protocols and experimental insights to facilitate seamless integration into ongoing research projects.
For researchers and clinicians looking to uncover the intricate roles of genes in health and disease, the STK36 Gene Knockout Cell Lines represent a powerful tool for advancing scientific discovery. Our company, backed by years of expertise in genetic modification and cellular technologies, is committed to providing high-quality products that empower researchers to push the boundaries of biological science.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.