ACVR1B Knockout cell line (HCT 116)

Catalog Number: KO11602

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Specifications

Product Information
Product Name	ACVR1B Knockout cell line (HCT 116)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:2~1:4
species	Human
Gene	ACVR1B
Gene ID	91
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90%McCOYs 5A+10% FBS
Parental Cell Line	HCT 116
Quality Control	Genotype: ACVR1B Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	activin A receptor type 1Bprovided by HGNC
Also known as	ALK4; SKR2; ACTRIB; ACVRLK4
Gene Description	This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
Expression	Ubiquitous expression in kidney (RPKM 15.7), colon (RPKM 11.9) and 25 other tissues See more

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