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MLXIPL Knockout cell line (HCT 116)

Catalog Number: KO06262

Price: Online Inquiry

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Specifications

Product Information
Product Name MLXIPL Knockout cell line (HCT 116)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:2~1:4
species Human
Gene MLXIPL
Gene ID 51085
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%McCOYs 5A+10% FBS
Parental Cell Line HCT 116
Quality Control Genotype: MLXIPL Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name MLX interacting protein likeprovided by HGNC
Also known as MIO; MLX; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14
Gene Description This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Expression Biased expression in fat (RPKM 35.0), liver (RPKM 27.7) and 8 other tissues See more

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