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LYRM1 Knockout cell line (A549)

Catalog Number: KO16404

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Specifications

Product Information
Product Name LYRM1 Knockout cell line (A549)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:4
species Human
Gene LYRM1
Gene ID 57149
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90% F12K+10% FBS
Parental Cell Line A549
Quality Control Genotype: LYRM1 Knockout cell line (A549) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name LYR motif containing 1provided by HGNC
Also known as A211C6.1
Gene Description The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Expression Ubiquitous expression in liver (RPKM 13.3), fat (RPKM 11.4) and 25 other tissues See more

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