KLHL24 Knockout cell line (HEK293)

Catalog Number: KO16669

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Specifications

Product Information
Product Name	KLHL24 Knockout cell line (HEK293)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:3~1:6
species	Human
Gene	KLHL24
Gene ID	54800
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90%DMEM+10% FBS
Parental Cell Line	HEK293
Quality Control	Genotype: KLHL24 Knockout cell line (HEK293) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	kelch like family member 24provided by HGNC
Also known as	DRE1; EBS6; CMH29; EBSSH; KRIP6
Gene Description	The protein encoded by this gene is a ubiquitin ligase substrate receptor and is regulated by autoubiquitination. Variations in the translation initiation codon of this gene have been found, which result in an N-terminally truncated but more stable protein due to loss of the autoubiquitination function. The more stable mutant protein causes an increased ubiquitin and degradation of keratin 14, which leads to skin fragility and the potentially life-threatening disease epidermolysis bullosa. The encoded protein is also involved in the regulation of kainate receptors. [provided by RefSeq, Mar 2017]
Expression	Ubiquitous expression in heart (RPKM 9.5), thyroid (RPKM 9.3) and 25 other tissues See more

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