CBFA2T3 Knockout cell line (HCT 116)

Catalog Number: KO38685

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Specifications

Product Information
Product Name	CBFA2T3 Knockout cell line (HCT 116)
specification	1*10^6
Storage and transportation	Dry ice preservation/T25 live cell transportation.
Cell morphology	Epithelioid, adherent cell
Passage ratio	1:2~1:4
species	Human
Gene	CBFA2T3
Gene ID	863
Build method	Electric rotation method / virus method
Mycoplasma testing	Negative
Cultivation system	90%McCOYs 5A+10% FBS
Parental Cell Line	HCT 116
Quality Control	Genotype: CBFA2T3 Knockout cell line (HCT 116) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.

Gene Information
Gene Official Full Name	CBFA2/RUNX1 partner transcriptional co-repressor 3provided by HGNC
Also known as	ETO2; MTG16; MTGR2; ZMYND4; RUNX1T3
Gene Description	This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Expression	Broad expression in spleen (RPKM 6.2), lymph node (RPKM 3.7) and 24 other tissues See more

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