Gene: ZZEF1
Official Full Name: zinc finger ZZ-type and EF-hand domain containing 1provided by HGNC
Gene Summary: Enables histone reader activity; lysine-acetylated histone binding activity; and methylated histone binding activity. Predicted to be involved in chromatin organization. Predicted to act upstream of or within several processes, including glutamatergic synaptic transmission; regulation of peptidyl-tyrosine phosphorylation; and visual learning. Predicted to be located in cell surface; postsynapse; and presynaptic active zone. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09816 | ZZEF1 Knockout cell line (HeLa) | Human | ZZEF1 | 1:3~1:6 | Negative | Online Inquiry |
KO09817 | ZZEF1 Knockout cell line (HCT 116) | Human | ZZEF1 | 1:2~1:4 | Negative | Online Inquiry |
KO09818 | ZZEF1 Knockout cell line (HEK293) | Human | ZZEF1 | 1:3~1:6 | Negative | Online Inquiry |
KO09819 | ZZEF1 Knockout cell line (A549) | Human | ZZEF1 | 1:3~1:4 | Negative | Online Inquiry |
ZZEF1 Gene Knockout Cell Lines are specifically engineered cellular models that lack functional ZZEF1 gene expression due to targeted gene editing techniques such as CRISPR-Cas9. These cell lines facilitate the detailed study of ZZEF1's role in various pathological and physiological processes, providing researchers with a powerful tool to interrogate the gene’s functions, regulatory mechanisms, and its contribution to cellular behavior.
The primary mechanism by which ZZEF1 knockout cell lines operate hinges on the complete abrogation of ZZEF1 protein production, allowing scientists to observe phenotypic changes, signaling pathway alterations, and gene expression profiles in the absence of this critical protein. This unique approach enables high-resolution studies of processes such as cell proliferation, apoptosis, and differentiation, as well as the evaluation of drug efficacy in the context of ZZEF1 modulation.
The scientific importance of these cell lines is profound, particularly in cancer research and therapeutic development, where ZZEF1 has been implicated in tumor progression and metastasis. Researchers can leverage these knockout lines to uncover mechanisms of drug resistance, elucidate the pathways influencing tumor behavior, and assess potential therapeutic interventions in pre-clinical models.
Compared to conventional methods or non-specific knockdown approaches, ZZEF1 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility, leading to more accurate results. These cell lines present a more reliable model than those created with transient silencing techniques, thus increasing the credibility and reproducibility of experimental data.
The value of ZZEF1 Gene Knockout Cell Lines extends beyond basic research; they provide clinicians and pharmaceutical scientists with a robust platform for understanding disease mechanisms and developing targeted therapies. Researchers and clinicians can gain critical insights that can expedite drug development and improve patient outcomes substantially.
Our commitment at [Your Company's Name] to innovation and excellence in biotechnological research underpins the development of these advanced cell line models. We prioritize quality and precision, ensuring that our products meet the highest standards of scientific research. By choosing our ZZEF1 Gene Knockout Cell Lines, you equip your research with cutting-edge tools that help push the boundaries of discovery and therapeutic advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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