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ZSCAN22 Knockout Cell Lines

Gene: ZSCAN22

Official Full Name: zinc finger and SCAN domain containing 22provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11876 ZSCAN22 Knockout cell line (HeLa) Human ZSCAN22 1:3~1:6 Negative Online Inquiry
KO11877 ZSCAN22 Knockout cell line (HCT 116) Human ZSCAN22 1:2~1:4 Negative Online Inquiry
KO11878 ZSCAN22 Knockout cell line (HEK293) Human ZSCAN22 1:3~1:6 Negative Online Inquiry
KO11879 ZSCAN22 Knockout cell line (A549) Human ZSCAN22 1:3~1:4 Negative Online Inquiry

Background

ZSCAN22 Gene Knockout Cell Lines are a specialized set of cellular models designed to allow researchers to investigate the biological functions of the ZSCAN22 gene, a critical regulator believed to play roles in immunological responses and various cellular processes. These knockout cell lines are created using advanced CRISPR/Cas9 technology, which enables precise editing of the genome to effectively disable the ZSCAN22 gene. By providing a cellular context devoid of ZSCAN22 activity, these models facilitate an in-depth analysis of gene function, cellular signaling pathways, and potential therapeutic targets.

The primary mechanism behind the ZSCAN22 Gene Knockout Cell Lines involves the introduction of a double-strand break at the ZSCAN22 locus, followed by the cell's natural repair processes that result in insertions or deletions (indels) that disrupt gene expression. This targeted approach allows researchers to observe the resultant phenotypic changes, providing insights into ZSCAN22’s role in cellular functions related to immune modulation and oncogenesis.

The scientific importance of these cell lines is underscored by their versatility in both research and clinical applications, particularly in the fields of oncology, immunology, and genetic disorders. These models enable researchers to elucidate the gene’s involvement in disease pathology, evaluate potential drug candidates, and assess therapeutic interventions that could mitigate the effects of ZSCAN22 dysfunction.

One of the significant advantages of ZSCAN22 Gene Knockout Cell Lines is their precise gene-targeting capability, which outperforms traditional methods such as siRNA or shRNA knockdown that may only reduce activity rather than completely eliminate it. This complete knockout allows for more rigorous testing of hypotheses and drug responses, setting a higher standard for experimental reproducibility and reliability.

For researchers, clinicians, and biopharmaceutical companies, ZSCAN22 Gene Knockout Cell Lines represent a valuable tool that can lead to breakthroughs in understanding disease mechanisms and developing new therapies. By leveraging these advanced models, users can accelerate their research timelines and enhance the quality of their findings.

Our company prides itself on being at the forefront of genetic research tools, providing meticulously validated biological products that empower scientists worldwide. Our commitment to excellence and innovation in the field of gene editing ensures that researchers have access to the best resources for their pioneering work.

Please note that all services are for research use only. Not intended for any clinical use.

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