Gene: ZNF892
Official Full Name: zinc finger protein 892provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11898 | ZNF892 Knockout cell line (HeLa) | Human | ZNF892 | 1:3~1:6 | Negative | Online Inquiry |
KO11899 | ZNF892 Knockout cell line (HCT 116) | Human | ZNF892 | 1:2~1:4 | Negative | Online Inquiry |
KO11900 | ZNF892 Knockout cell line (HEK293) | Human | ZNF892 | 1:3~1:6 | Negative | Online Inquiry |
KO11901 | ZNF892 Knockout cell line (A549) | Human | ZNF892 | 1:3~1:4 | Negative | Online Inquiry |
ZNF892 Gene Knockout Cell Lines are genetically modified cell lines designed to facilitate the study of the ZNF892 gene's functions in various biological processes. By employing precise CRISPR-Cas9 genome editing technology, these cell lines have been developed to eliminate the expression of ZNF892, offering a powerful tool for researchers investigating its roles in cellular mechanisms, differentiation, and potential disease implications.
The primary function of ZNF892 knockout cell lines is to provide a platform for functional genomics studies, allowing scientists to observe the phenotypic consequences of ZNF892 deletion. This enables researchers to analyze alterations in cellular pathways, gene expression profiles, and response to stimuli, affording insights into the gene’s role in health and disease. Moreover, by utilizing these cell lines in high-throughput screening assays, researchers can identify potential therapeutic targets for conditions linked to abnormal ZNF892 activity, including certain cancers and neurodegenerative disorders.
The scientific importance of ZNF892 knockout cell lines is underscored by their application in both basic and translational research settings. They serve as essential models for understanding gene function and regulation, contributing to the elucidation of molecular mechanisms underlying complex diseases. Furthermore, these cell lines facilitate the evaluation of pharmacological interventions, making them invaluable for drug discovery and development.
Compared to other gene knockout models, the ZNF892 knockout cell lines offer enhanced specificity and efficiency due to their precise genetic modification. This leads to reduced off-target effects and more reliable experimental outcomes. Additionally, the availability of these cell lines in various cellular contexts, such as stem cells and differentiated cell types, provides researchers with flexibility in modeling specific biological scenarios.
For researchers and clinicians dedicated to unraveling the complexities of gene functions and their implications in disease, ZNF892 knockout cell lines represent a valuable resource. Their ability to yield reproducible and insightful data equips scientists to push the boundaries of current knowledge and accelerate the development of innovative therapies.
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Please note that all services are for research use only. Not intended for any clinical use.
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