Gene: ZNF865
Official Full Name: zinc finger protein 865provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11917 | ZNF865 Knockout cell line (HeLa) | Human | ZNF865 | 1:3~1:6 | Negative | Online Inquiry |
KO11918 | ZNF865 Knockout cell line (HCT 116) | Human | ZNF865 | 1:2~1:4 | Negative | Online Inquiry |
KO11919 | ZNF865 Knockout cell line (HEK293) | Human | ZNF865 | 1:3~1:6 | Negative | Online Inquiry |
KO11920 | ZNF865 Knockout cell line (A549) | Human | ZNF865 | 1:3~1:4 | Negative | Online Inquiry |
ZNF865 Gene Knockout Cell Lines are specialized cellular models engineered to effectively disable the ZNF865 gene, a member of the zinc-finger protein family, which is associated with various cellular functions including gene expression regulation and potentially neurological disorders. The process of gene knockout involves targeted disruption of the gene's coding sequence, leading to a loss-of-function phenotype. These cell lines are pivotal for studying the biological roles of ZNF865 in cellular mechanisms, including embryonic development, neuronal function, and disease pathology.
The primary function of ZNF865 knockout cell lines is to provide a clear genetic background to investigate the effects of ZNF865 deficiency. By utilizing CRISPR-Cas9 or TALEN technologies for gene editing, researchers can create precise models that allow for the exploration of gene function, interaction with other cellular pathways, and response to pharmacological agents. This is particularly significant in the context of understanding neurodevelopmental and neurodegenerative diseases linked to aberrant ZNF865 expression.
In clinical and research settings, the importance of ZNF865 gene knockout cell lines cannot be overstated. They serve as invaluable tools for drug discovery, allowing scientists to assess the impact of potential therapeutics in a controlled environment. Additionally, these models facilitate the identification of novel biomarkers and therapeutic targets, crucial for advancing personalized medicine.
One of the main advantages of ZNF865 knockout cell lines is their specificity, which surpasses many traditional approaches that often yield ambiguous results. Compared to alternative models, these engineered cell lines offer a consistent genetic background that eliminates variability, enabling researchers to conduct reproducible experiments. This reliability is essential for achieving robust scientific outcomes and facilitates the translation of findings from the bench to the clinic.
In summary, ZNF865 Gene Knockout Cell Lines represent a cutting-edge solution for researchers and clinicians aiming to elucidate the complex roles of the ZNF865 gene. With our company’s commitment to developing high-quality biological products backed by extensive expertise in gene editing technologies, we offer a reliable resource that enhances research efficiency and contributes to breakthrough discoveries in genetics and molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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