Gene: ZNF747
Official Full Name: zinc finger protein 747provided by HGNC
Gene Summary: Predicted to enable metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12019 | ZNF747 Knockout cell line (HeLa) | Human | ZNF747 | 1:3~1:6 | Negative | Online Inquiry |
KO12020 | ZNF747 Knockout cell line (HCT 116) | Human | ZNF747 | 1:2~1:4 | Negative | Online Inquiry |
KO12021 | ZNF747 Knockout cell line (HEK293) | Human | ZNF747 | 1:3~1:6 | Negative | Online Inquiry |
KO12022 | ZNF747 Knockout cell line (A549) | Human | ZNF747 | 1:3~1:4 | Negative | Online Inquiry |
ZNF747 Gene Knockout Cell Lines are innovative research tools designed for the study of gene function and regulation within various biological contexts. These genetically modified cell lines provide an essential platform for investigating the role of the ZNF747 gene, known to be implicated in crucial cellular processes such as apoptosis, cell cycle regulation, and oncogenesis. Utilizing CRISPR-Cas9 technology, the ZNF747 gene has been precisely edited to create knockout variants, thereby facilitating the exploration of the specific phenotypic and molecular consequences associated with its loss of function.
The primary mechanism of action involves the targeted disruption of the ZNF747 gene, resulting in the prevention of transcription of its mRNA and, consequently, the synthesis of its protein product. This allows researchers to observe the downstream effects on cellular behavior and signaling pathways, offering insights into the molecular underpinnings of disease mechanisms, especially in cancer research. The study of these knockout cell lines is imperative in elucidating gene functions and pathways, which can contribute to the development of targeted therapeutic strategies.
In terms of scientific importance, ZNF747 Gene Knockout Cell Lines are valuable assets in both academic and clinical research settings. They are being utilized to validate ZNF747 as a potential biomarker for tumor progression and therapeutic resistance, potentially paving the way for novel intervention strategies. Compared to alternative models, our ZNF747 knockout lines provide enhanced reproducibility and specificity, reducing the risk of off-target effects, while offering a fully characterized genetic background for reliable experimental outcomes.
Researchers and clinicians will find these cell lines indispensable, as they streamline the investigation into gene function and promote discoveries that can translate to clinical applications. With our extensive expertise in genetic engineering and cell line development, we stand committed to providing high-quality biological products that empower scientific advancement and foster innovation in research efforts.
Please note that all services are for research use only. Not intended for any clinical use.
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