Gene: ZNF738
Official Full Name: zinc finger protein 738provided by HGNC
Gene Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23493 | ZNF738 Knockout cell line (HeLa) | Human | ZNF738 | 1:3~1:6 | Negative | Online Inquiry |
KO23494 | ZNF738 Knockout cell line (HCT 116) | Human | ZNF738 | 1:2~1:4 | Negative | Online Inquiry |
KO23495 | ZNF738 Knockout cell line (HEK293) | Human | ZNF738 | 1:3~1:6 | Negative | Online Inquiry |
KO23496 | ZNF738 Knockout cell line (A549) | Human | ZNF738 | 1:3~1:4 | Negative | Online Inquiry |
ZNF738 Gene Knockout Cell Lines are specifically engineered cell lines designed to lack the expression of the ZNF738 gene, a key regulator involved in various cellular processes, including gene expression, cell differentiation, and apoptosis. These genetically modified cell lines serve as crucial tools for understanding the functional implications of ZNF738 in both normal physiology and pathological conditions.
The primary function of ZNF738 gene knockout cell lines is to enable researchers to investigate the biological consequences of ZNF738 deficiency. By utilizing CRISPR-Cas9 or similar genome editing technologies, these cell lines exhibit significant alterations in pathways related to cellular growth, response to stress, and metabolic processes, thus providing invaluable insights into the gene’s role in cancer biology and other diseases. The absence of ZNF738 allows for the assessment of downstream signaling pathways and potential compensatory mechanisms that may arise in its absence.
The scientific importance of these knockout cell lines lies in their applicability in both research and clinical settings. In cancer research, for instance, ZNF738 has been associated with tumor progression, making these cell lines pivotal for drug discovery and the exploration of novel therapeutic targets. Moreover, they can provide insights into genetic diseases linked to dysregulated gene expression and cellular dysfunction.
Compared to alternative models, such as wild-type cell lines or animal models, ZNF738 gene knockout cell lines offer higher specificity and control over genetic alterations, resulting in more reproducible and reliable data. Their defined genetic background also allows for clearer interpretation of experimental outcomes.
For researchers and clinicians focusing on oncology, genetics, or cellular biology, ZNF738 Gene Knockout Cell Lines present a unique opportunity to delve deeper into gene function and disease mechanisms. Furthermore, the integration of detailed characterization and validation studies ensures that users are equipped with robust tools to achieve their research goals.
Our company, with its commitment to precision and innovation in biological products, stands at the forefront of genetic research. We provide expertly crafted knockout cell lines that not only meet the highest standards of quality but also empower the scientific community to explore uncharted territories in gene function and regulatory mechanisms.
Please note that all services are for research use only. Not intended for any clinical use.
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