Gene: ZNF677
Official Full Name: zinc finger protein 677provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12073 | ZNF677 Knockout cell line (HEK293) | Human | ZNF677 | 1:3~1:6 | Negative | Online Inquiry |
ZNF677 Gene Knockout Cell Lines are engineered cellular models designed to specifically disrupt the expression of the ZNF677 gene, which encodes a protein belonging to the zinc finger protein family. These cell lines serve as pivotal tools for researchers examining the gene's role in various biological processes, including gene regulation, cellular differentiation, and disease pathogenesis. By knocking out ZNF677, these cell lines allow for comprehensive studies on how its absence influences cellular behavior and interaction with external stimuli.
The primary mechanism of action involves the introduction of targeted gene-editing technologies, such as CRISPR-Cas9, to induce precise genomic alterations. This results in a complete loss of ZNF677 function, enabling investigators to explore the subsequent effects on signaling pathways, transcriptional responses, and phenotypic changes. Furthermore, ZNF677 gene knockout models can elucidate connections between gene dysregulation and the onset of diseases, including cancer, providing insights crucial for therapeutic strategies.
From a scientific standpoint, these cell lines are invaluable in both basic and applied research settings. They have the potential to uncover the biological significance of ZNF677 in disease mechanisms and contribute to the identification of novel therapeutic targets. Compared to alternatives, our ZNF677 Gene Knockout Cell Lines offer high specificity and reproducibility, ensuring robust and reliable data for your research.
Researchers and clinicians will find this product particularly valuable for its ability to facilitate advanced studies in gene function and mechanistic biology, ultimately driving forward the development of targeted therapies. With extensive expertise in gene editing and a commitment to quality, our company stands at the forefront of innovation, providing high-grade biological systems designed to accelerate the pace of discovery in molecular biology and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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