Gene: ZNF644
Official Full Name: zinc finger protein 644provided by HGNC
Gene Summary: The protein encoded by this gene is a zinc finger transcription factor that may play a role in eye development. Defects in this gene have been associated with high myopia. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00353 | ZNF644 Knockout cell line(ARPE-19) | Human | ZNF644 | 1:3~1:5 | Negative | Online Inquiry |
KO25155 | ZNF644 Knockout cell line (HeLa) | Human | ZNF644 | 1:3~1:6 | Negative | Online Inquiry |
KO25156 | ZNF644 Knockout cell line (HCT 116) | Human | ZNF644 | 1:2~1:4 | Negative | Online Inquiry |
KO25157 | ZNF644 Knockout cell line (HEK293) | Human | ZNF644 | 1:3~1:6 | Negative | Online Inquiry |
KO25158 | ZNF644 Knockout cell line (A549) | Human | ZNF644 | 1:3~1:4 | Negative | Online Inquiry |
ZNF644 Gene Knockout Cell Lines are genetically modified cell models that have been specifically engineered to excise the ZNF644 gene, which encodes a zinc finger protein involved in the regulation of diverse biological processes, including transcriptional control and chromatin remodeling. These cell lines serve as invaluable tools for elucidating the functional roles of ZNF644 in cellular pathways and disease states.
The primary mechanism of the ZNF644 gene knockout involves the application of CRISPR-Cas9 technology, a powerful genome editing system that enables precise deletion of target DNA sequences. By removing the ZNF644 gene, researchers can investigate its contributions to cellular behavior, including differentiation, proliferation, and responses to environmental stimuli. This targeted approach facilitates the study of ZNF644's roles in critical conditions such as cancer, neurodegeneration, and metabolic disorders, allowing for the identification of potential therapeutic targets.
The scientific importance of ZNF644 Gene Knockout Cell Lines cannot be overstated; they provide a crucial platform for insights into gene function and the implications of gene dysregulation in disease. These models are particularly relevant in research settings focused on functional genomics and personalized medicine. They can aid in drug development by enabling screening for compounds that can modulate pathways influenced by ZNF644.
What sets ZNF644 Gene Knockout Cell Lines apart from alternative cellular models is their specificity and versatility. Unlike overexpression systems or knockdown approaches that may yield ambiguous results, permanent knockout lines offer a clean and stable genetic background to study the specific effects of the gene loss. This clarity enhances data reliability and reproducibility in experimental research.
For researchers and clinicians, the availability of ZNF644 Gene Knockout Cell Lines presents a significant opportunity to deepen our understanding of gene function and its therapeutic implications. By incorporating these cell lines into their studies, users can accelerate discoveries in the realms of gene therapy, regenerative medicine, and oncology.
Our company prides itself on its commitment to advancing biological research through innovative genetic tools. With extensive expertise in gene editing technologies and a robust portfolio of specialized cell lines, we empower scientists by providing high-quality models that facilitate transformative research outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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