Gene: ZNF639
Official Full Name: zinc finger protein 639provided by HGNC
Gene Summary: This gene encodes a member of the Kruppel-like zinc finger family of proteins. Amplification and overexpression of this gene have been observed in esophageal squamous cell carcinoma. The encoded protein has been shown to bind DNA in a sequence-specific manner and may regulate HIV-1 gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22882 | ZNF639 Knockout cell line (HeLa) | Human | ZNF639 | 1:3~1:6 | Negative | Online Inquiry |
KO22883 | ZNF639 Knockout cell line (HCT 116) | Human | ZNF639 | 1:2~1:4 | Negative | Online Inquiry |
KO22884 | ZNF639 Knockout cell line (HEK293) | Human | ZNF639 | 1:3~1:6 | Negative | Online Inquiry |
KO22885 | ZNF639 Knockout cell line (A549) | Human | ZNF639 | 1:3~1:4 | Negative | Online Inquiry |
ZNF639 Gene Knockout Cell Lines are specially engineered cellular models that serve as powerful tools for investigating the biological functions of the ZNF639 gene. This gene encodes a zinc-finger protein involved in transcriptional regulation, with implications in various cellular processes, including differentiation, proliferation, and apoptosis. By effectively knocking out the ZNF639 gene, these cell lines enable researchers to study the gene's role in various physiological and pathological conditions, thereby facilitating a deeper understanding of its contributions to human health and disease.
The key function of ZNF639 Gene Knockout Cell Lines lies in their ability to eliminate the expression of ZNF639, allowing for the dissection of its downstream signaling pathways and biological interactions. This knockout model provides a clean slate, inherent in its design, to assess gene functions without the confounding effects of residual expression. Moreover, it supports the elucidation of gene-gene interactions and the impact of ZNF639 loss on cellular behavior, making it highly valuable for both basic and applied research.
From a scientific standpoint, these cell lines are instrumental in studies related to cancer biology, neurodevelopmental disorders, and other diseases where ZNF639 may play a pivotal role. They offer significant advantages in drug discovery and therapeutic interventions, enabling researchers to develop targeted strategies with the potential for precision medicine applications.
When compared to traditional gene silencing techniques, such as RNA interference, ZNF639 Gene Knockout Cell Lines provide more stable and permanent gene editing, yielding results that are reproducible and reliable over extended experimentation periods. This stability ensures that the data collected is robust, reducing variability due to transient knockdowns.
For researchers and clinicians, the ZNF639 Gene Knockout Cell Lines stand out as invaluable resources, enhancing experimental throughput and aiding in the swift identification of therapeutic targets and biomarkers. Our company prides itself on a commitment to innovation and excellence in genetic engineering, ensuring that our products meet the highest standards of quality and usability in the field of molecular biology and genetic research.
Please note that all services are for research use only. Not intended for any clinical use.
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