Gene: ZNF614
Official Full Name: zinc finger protein 614provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26235 | ZNF614 Knockout cell line (HeLa) | Human | ZNF614 | 1:3~1:6 | Negative | Online Inquiry |
KO26236 | ZNF614 Knockout cell line (HCT 116) | Human | ZNF614 | 1:2~1:4 | Negative | Online Inquiry |
KO26237 | ZNF614 Knockout cell line (HEK293) | Human | ZNF614 | 1:3~1:6 | Negative | Online Inquiry |
KO26238 | ZNF614 Knockout cell line (A549) | Human | ZNF614 | 1:3~1:4 | Negative | Online Inquiry |
ZNF614 Gene Knockout Cell Lines represent a powerful tool in gene function studies and cell biology, specifically designed to aid researchers in exploring the roles of the ZNF614 gene in various cellular processes. This product consists of vertebrate cell lines engineered to have a specific deletion of the ZNF614 gene, enabling detailed investigation into its biological implications. These knockout models are pivotal for elucidating the gene's contributions to phenomena such as cell differentiation, proliferation, and response to stress.
The primary mechanism at play involves the targeted disruption of the ZNF614 gene through CRISPR-Cas9 technology, which ensures a precise alteration of the genomic landscape. By generating these knockout cell lines, researchers can observe the resultant phenotypic changes, allowing for in-depth analyses of downstream signaling pathways and functional outcomes. This has profound implications in both fundamental biological research and translational medicine, particularly in understanding diseases linked to dysregulation of ZNF614.
The scientific importance of ZNF614 Gene Knockout Cell Lines cannot be overstated. They serve as essential models for studying neurodevelopmental disorders, cancer biology, and responses to therapeutic interventions. In clinical settings, they can accelerate the discovery of targeted treatments and biomarkers by elucidating the functional characteristics of ZNF614 within pathophysiological contexts.
One of the substantial advantages of our ZNF614 Gene Knockout Cell Lines lies in their robustness and high reproducibility, ensuring reliable results across experiments. Unlike less specific methods such as RNA interference, which can lead to off-target effects, our knockout lines offer a definitive approach to gene manipulation with minimal complications. This specificity paves the way for more accurate interpretations of experimental data, making our product particularly valuable for researchers and clinicians committed to advancing their work.
For laboratories and institutions aiming to push the boundaries of genetic research, ZNF614 Gene Knockout Cell Lines offer invaluable insight and innovation potential. Backed by a team of experts in genetic engineering and cell biology, our company is dedicated to providing high-quality biological products that support the scientific community's quest for knowledge and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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