Gene: ZNF518A
Official Full Name: zinc finger protein 518Aprovided by HGNC
Gene Summary: The protein encoded by this gene is a member of the krueppel C2H2-type zinc finger protein family. The encoded protein contains five zinc fingers and is likely a nuclear transcriptional regulator. Numerous transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32658 | ZNF518A Knockout cell line (HeLa) | Human | ZNF518A | 1:3~1:6 | Negative | Online Inquiry |
KO32659 | ZNF518A Knockout cell line (HCT 116) | Human | ZNF518A | 1:2~1:4 | Negative | Online Inquiry |
KO32660 | ZNF518A Knockout cell line (HEK293) | Human | ZNF518A | 1:3~1:6 | Negative | Online Inquiry |
KO32661 | ZNF518A Knockout cell line (A549) | Human | ZNF518A | 1:3~1:4 | Negative | Online Inquiry |
ZNF518A Gene Knockout Cell Lines are genetically engineered cell lines that have been developed to specifically delete the ZNF518A gene, which encodes a zinc finger protein involved in various cellular processes, including transcription regulation and signal transduction pathways. These knockout models provide valuable tools for studying the gene's function and its implications in diseases, particularly cancer.
The primary function of ZNF518A knockout cell lines is to facilitate the investigation of gene loss-of-function effects, allowing researchers to elucidate the biological roles of the ZNF518A gene in cellular physiology and pathophysiology. Mechanistically, these cell lines enable the analysis of cellular signaling cascades, gene expression profiles, and phenotypic changes that occur in the absence of ZNF518A, thus providing crucial insights into its contributions to disease states.
Scientifically, ZNF518A knockout cell lines hold significant importance in both basic and translational research. They can be employed in studies examining the molecular mechanisms underlying tumorigenesis, responses to chemotherapeutics, and the regulation of immune responses. Moreover, they can assist in developing novel therapeutic strategies aimed at targeting pathways modulated by ZNF518A.
Compared to traditional gene silencing methods, such as RNA interference, the use of knockout cell lines offers a more definitive approach to understanding gene function. The knockout models provide a complete absence of the target protein, leading to fewer off-target effects and more robust experimental outcomes. Furthermore, these cell lines can typically be utilized across various experimental conditions, making them versatile tools in laboratories.
Researchers and clinicians will find ZNF518A gene knockout cell lines invaluable for advancing their understanding of gene function and disease mechanisms. Their precision and reliability contribute to the generation of reproducible data that can facilitate innovation in therapeutic development.
Our company specializes in the creation and supply of genetically modified cell lines, backed by extensive expertise in molecular biology and genetics. We are committed to supporting scientific research through high-quality, ready-to-use models that empower researchers to unlock the complexities of human biology.
Please note that all services are for research use only. Not intended for any clinical use.
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