Gene: ZNF503
Official Full Name: zinc finger protein 503provided by HGNC
Gene Summary: Predicted to enable metal ion binding activity. Involved in G1 to G0 transition involved in cell differentiation; negative regulation of cell population proliferation; and negative regulation of gene expression. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24587 | ZNF503 Knockout cell line (HeLa) | Human | ZNF503 | 1:3~1:6 | Negative | Online Inquiry |
KO24588 | ZNF503 Knockout cell line (HCT 116) | Human | ZNF503 | 1:2~1:4 | Negative | Online Inquiry |
KO24589 | ZNF503 Knockout cell line (HEK293) | Human | ZNF503 | 1:3~1:6 | Negative | Online Inquiry |
KO24590 | ZNF503 Knockout cell line (A549) | Human | ZNF503 | 1:3~1:4 | Negative | Online Inquiry |
ZNF503 Gene Knockout Cell Lines are innovative biological tools specifically designed to facilitate the study of gene function and regulation in cellular contexts. These cell lines have been genetically modified to lack the ZNF503 gene, which encodes a zinc finger protein implicated in various cellular processes, including transcriptional regulation and developmental biology. By providing a controlled environment in which the effects of ZNF503 depletion can be observed, these knockout cell lines enable researchers to dissect the specific roles of this gene in pathways related to cell growth, differentiation, and responses to external stimuli.
The ZNF503 Gene Knockout Cell Lines operate through the principle of gene disruption, achieved using CRISPR-Cas9 technology, which allows for precise edits in the genome. This mechanism results in a complete abrogation of ZNF503 expression, allowing for in-depth analysis of resultant phenotypic changes. Researchers can leverage these knockout models to elucidate the molecular mechanisms underpinning diseases, particularly those involving dysregulation of gene expression.
The significance of these cell lines extends to both basic and translational research, making them invaluable tools in the fields of oncology, developmental biology, and genetics. Their application spans from studying gene function and interaction networks to testing therapeutic compounds aimed at restoring the functions lost due to ZNF503 knockout.
When compared to alternative methodologies, the ZNF503 Gene Knockout Cell Lines stand out due to their specificity, reproducibility, and the ease with which they can be integrated into existing experimental workflows. These cells provide a robust platform for high-throughput screening and functional assays, accelerating the pace of discovery while ensuring the validity of research findings.
For researchers, clinicians, and academic institutions, the availability of ZNF503 Gene Knockout Cell Lines represents a significant advancement in understanding gene function and disease mechanisms. Their implementation can lead to critical insights that inform therapeutic strategies and foster innovation in clinical approaches.
As a leader in the biotechnology field, our company is dedicated to providing high-quality, validated biological products that empower scientific research. We leverage our expertise to continuously innovate and enhance our product offerings, ensuring that researchers have access to the best tools available to drive their discoveries forward.
Please note that all services are for research use only. Not intended for any clinical use.
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