Gene: ZNF483
Official Full Name: zinc finger protein 483provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12206 | ZNF483 Knockout cell line (HeLa) | Human | ZNF483 | 1:3~1:6 | Negative | Online Inquiry |
KO12207 | ZNF483 Knockout cell line (HCT 116) | Human | ZNF483 | 1:2~1:4 | Negative | Online Inquiry |
KO12208 | ZNF483 Knockout cell line (HEK293) | Human | ZNF483 | 1:3~1:6 | Negative | Online Inquiry |
KO12209 | ZNF483 Knockout cell line (A549) | Human | ZNF483 | 1:3~1:4 | Negative | Online Inquiry |
ZNF483 Gene Knockout Cell Lines are a revolutionary biotechnological product designed for advanced genomic research, specifically focusing on the functional investigation of the ZNF483 gene. These cell lines have been meticulously engineered using CRISPR/Cas9 technology to achieve precise targeting and knockout of the ZNF483 gene, allowing researchers to study its role in cellular processes and disease pathways. The knockouts effectively eliminate the expression of the ZNF483 protein, enabling an in-depth analysis of its functional contributions in various biological contexts.
The key mechanism behind the functionality of these cell lines is the application of CRISPR/Cas9, a powerful genome-editing tool that employs a guide RNA to direct the Cas9 endonuclease to a specific genomic location. This results in double-strand breaks that, when repaired by the cell's natural mechanisms, lead to insertions or deletions in the ZNF483 gene, effectively knocking it out. This technology not only facilitates the exploration of gene function but also allows the investigation of gene-environment interactions, making it crucial for both fundamental and applied research.
In the scientific community, ZNF483 has been implicated in several biological processes, including transcriptional regulation and cellular differentiation. Therefore, these knockout cell lines are invaluable in various research fields, including cancer biology, stem cell research, and developmental biology. Their application in clinical settings can also aid in identifying novel therapeutic targets and understanding disease mechanisms, potentially translating into innovative treatment strategies.
What sets ZNF483 Gene Knockout Cell Lines apart from alternative products is the high specificity and efficiency of our CRISPR/Cas9 design, coupled with rigorous validation processes that ensure the reliability of results. These lines are extensively validated for genetic integrity and functional competency, which provides users with confidence in their experimental outcomes.
Researchers and clinicians alike will recognize the value of these knockout cell lines as essential tools for elucidating the complexities of gene function, enhancing their experimental repertoire and driving forward their discoveries. By utilizing our expertly developed ZNF483 Gene Knockout Cell Lines, you gain access to cutting-edge technology that empowers your research endeavors.
At [Your Company Name], we pride ourselves on our commitment to innovation and excellence in the field of biological products, dedicating ourselves to providing high-quality research tools that meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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