Gene: ZNF468
Official Full Name: zinc finger protein 468provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23781 | ZNF468 Knockout cell line (HeLa) | Human | ZNF468 | 1:3~1:6 | Negative | Online Inquiry |
KO23782 | ZNF468 Knockout cell line (HCT 116) | Human | ZNF468 | 1:2~1:4 | Negative | Online Inquiry |
KO23783 | ZNF468 Knockout cell line (HEK293) | Human | ZNF468 | 1:3~1:6 | Negative | Online Inquiry |
KO23784 | ZNF468 Knockout cell line (A549) | Human | ZNF468 | 1:3~1:4 | Negative | Online Inquiry |
ZNF468 Gene Knockout Cell Lines are highly specialized cellular models engineered to facilitate the in-depth study of the Zinc Finger protein 468 (ZNF468) and its implications in various biological processes. These cell lines are created using CRISPR-Cas9 gene editing technology to produce specific deletions in the ZNF468 gene, allowing researchers to effectively investigate the gene's role in cellular signaling, differentiation, and response to external stimuli.
The primary mechanism of action involves the CRISPR-Cas9 system, which induces double-strand breaks at the target DNA site, followed by precise editing to create the knockout phenotype. By comparing the ZNF468 knockout cells with wild-type counterparts, researchers can elucidate the functional consequences of ZNF468 deficiency, contributing to a greater understanding of its biological roles, particularly in cancer biology and developmental processes.
Clinically, ZNF468 knockout cell lines hold significant promise for advancing research in genetic disorders and therapeutic interventions. The investigation of this gene's role can aid in identifying novel biomarkers and potential therapeutic targets, thus enhancing the ability to devise targeted treatments in oncology and regenerative medicine.
What sets our ZNF468 Gene Knockout Cell Lines apart from alternatives is not only their high efficiency and specificity in gene editing but also the comprehensive characterizations and validations provided alongside, ensuring reliability in experimental results. Researchers can leverage these cell lines to save time and resources while gaining insights into complex genetic interactions.
The value proposition for researchers and clinicians lies in the potential of these knockout models to streamline experimental workflows, enhance reproducibility, and uncover critical genetic information that could be transformative for understanding disease mechanisms. Our company, with extensive experience in genomic tools and a focus on quality assurance, is committed to supporting scientific innovation through state-of-the-art biological products designed for cutting-edge research.
Please note that all services are for research use only. Not intended for any clinical use.
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