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ZNF425 Knockout Cell Lines

Gene: ZNF425

Official Full Name: zinc finger protein 425provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12243 ZNF425 Knockout cell line (HCT 116) Human ZNF425 1:2~1:4 Negative Online Inquiry
KO12244 ZNF425 Knockout cell line (HEK293) Human ZNF425 1:3~1:6 Negative Online Inquiry
KO12245 ZNF425 Knockout cell line (A549) Human ZNF425 1:3~1:4 Negative Online Inquiry

Background

ZNF425 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the ZNF425 gene, a transcription factor implicated in various biological processes, including cell differentiation and chromatin remodeling. These knockout models allow researchers to observe the effects of ZNF425 loss-of-function directly in a controlled environment, providing insights into its role in development and disease states such as cancer.

The key function of ZNF425 gene knockout cell lines revolves around the complete ablation of ZNF425 gene activity. This is achieved through CRISPR-Cas9 technology, which introduces targeted double-strand breaks in the ZNF425 gene, effectively preventing its expression. By utilizing these knockout cell lines, scientists can assess the regulatory networks disrupted by the absence of ZNF425, thereby elucidating its downstream effects on gene expression, metabolic pathways, and cellular behavior.

Scientifically, ZNF425 gene knockout cell lines offer significant value in both research and clinical contexts. They serve as vital tools for investigating the molecular mechanisms of ZNF425 in various diseases, including its potential role in tumorigenesis or response to therapies. Additionally, these models enable the development of therapeutic strategies aimed at restoring or compensating for the loss of ZNF425 function.

Compared to traditional gene manipulation methods, ZNF425 gene knockout cell lines provide greater precision and reproducibility. Their use of cutting-edge gene-editing technology ensures high efficiency in generating specific knockouts, leading researchers to obtain reliable data with minimized off-target effects. Furthermore, the availability of these standardized cell lines enhances collaborative research efforts, as they offer a common platform for experimental validation across different laboratories.

For researchers and clinicians focused on the complexities of gene regulation and its implications in health and disease, ZNF425 gene knockout cell lines are an invaluable asset. They not only streamline experimental design but also empower scientists to unearth novel biological insights that could translate into therapeutic advancements.

Our company specializes in providing high-quality genetic research tools and is committed to advancing the frontiers of molecular biology. With our expertise in developing reliable gene knockout models, we aim to support researchers in their quest to unlock the mysteries of gene function and its implications in various biological contexts.

Please note that all services are for research use only. Not intended for any clinical use.

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