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ZNF419 Knockout Cell Lines

Gene: ZNF419

Official Full Name: zinc finger protein 419provided by HGNC

Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO12246 ZNF419 Knockout cell line (HeLa) Human ZNF419 1:3~1:6 Negative Online Inquiry
KO12247 ZNF419 Knockout cell line (HCT 116) Human ZNF419 1:2~1:4 Negative Online Inquiry
KO12248 ZNF419 Knockout cell line (HEK293) Human ZNF419 1:3~1:6 Negative Online Inquiry
KO12249 ZNF419 Knockout cell line (A549) Human ZNF419 1:3~1:4 Negative Online Inquiry

Background

ZNF419 Gene Knockout Cell Lines represent a cutting-edge tool for researchers engaged in genomics, cellular biology, and therapeutic development. These cell lines have been specifically engineered to inactivate the ZNF419 gene, a member of the zinc-finger protein family implicated in various biological processes and diseases. By utilizing CRISPR/Cas9 technology, our ZNF419 knockout lines provide a reliable and efficient way to study the functional consequences of ZNF419 loss, shedding light on its role in cellular pathways governing differentiation, proliferation, and apoptosis.

The primary mechanism of action revolves around the targeted disruption of the ZNF419 gene, which effectively eliminates its expression. This loss allows researchers to perform comprehensive functional assays, thereby elucidating ZNF419's involvement in key signaling pathways and its potential impact on cellular responses to external stimuli. Beyond basic research, understanding the role of ZNF419 may unveil novel therapeutic targets, particularly in oncology, where gene regulation is often derailed.

What sets our ZNF419 Gene Knockout Cell Lines apart from competitors is the high specificity and efficiency of the knockout achieved through optimized CRISPR design protocols, resulting in minimal off-target effects. Furthermore, our cell lines are rigorously validated for stability and reproducibility, ensuring that scientists can attain consistent results across experiments.

For researchers and clinicians, these cell lines serve as invaluable resources for functional genomics studies, drug discovery, and the development of precision medicine strategies. The ability to model specific genetic alterations allows for more accurate simulations of disease states, thus enhancing the translational potential of research findings.

Our company prides itself on its long-standing expertise in cellular and molecular biology, offering a diverse portfolio of knockout cell lines that empower the scientific community. With our commitment to quality and innovation, we strive to support groundbreaking research that ultimately accelerates the pace of discovery in various fields of biological sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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